IgG4-related Disease Manifesting as Gastroduodenal Ulcer Diagnosed by an Endoscopic Biopsy.


Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
15 Oct 2020
Historique:
pubmed: 26 6 2020
medline: 23 2 2021
entrez: 26 6 2020
Statut: ppublish

Résumé

A 26-year-old man was admitted to our hospital due to upper abdominal pain. He had previously been diagnosed with gastroduodenal ulcer at 23 and 25 years old and had been treated with proton-pump inhibitors. Endoscopic hemostasis and a biopsy were performed on the hemorrhagic gastroduodenal ulcers. Laboratory and pathologic examinations demonstrated elevated serum IgG4 levels and the infiltration of IgG4-positive plasma cells into the gastroduodenal tissues. Based on the clinicopathologic findings and after excluding other causes, he was diagnosed with IgG4-related gastroduodenal ulcer. We herein report a rare case of IgG4-related disease manifesting as a gastroduodenal ulcer diagnosed by an endoscopic biopsy.

Identifiants

pubmed: 32581158
doi: 10.2169/internalmedicine.4483-20
pmc: PMC7662039
doi:

Substances chimiques

Immunoglobulin G 0
Proton Pump Inhibitors 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2491-2497

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Auteurs

Osamu Muto (O)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

Susumu Tamakawa (S)

Department of Pathology, National Hospital Organization Asahikawa Medical Center, Japan.

Kenji Takahashi (K)

Division of Metabolism and Biosystemic Science, Department of Medicine, Asahikawa Medical University, Japan.

Shiro Yokohama (S)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

Ai Takasoe (A)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

Fuminori Hirano (F)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

Hideo Nishimura (H)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

Hiroki Saito (H)

Department of Gastroenterology, National Hospital Organization Asahikawa Medical Center, Japan.

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Classifications MeSH