Cellular locomotion using environmental topography.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
06 2020
Historique:
received: 13 01 2018
accepted: 09 03 2020
entrez: 26 6 2020
pubmed: 26 6 2020
medline: 21 10 2020
Statut: ppublish

Résumé

Eukaryotic cells migrate by coupling the intracellular force of the actin cytoskeleton to the environment. While force coupling is usually mediated by transmembrane adhesion receptors, especially those of the integrin family, amoeboid cells such as leukocytes can migrate extremely fast despite very low adhesive forces

Identifiants

pubmed: 32581372
doi: 10.1038/s41586-020-2283-z
pii: 10.1038/s41586-020-2283-z
doi:

Substances chimiques

Actins 0
Talin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

582-585

Subventions

Organisme : Austrian Science Fund FWF
ID : P 29911
Pays : Austria
Organisme : European Research Council
Pays : International

Commentaires et corrections

Type : CommentIn

Références

Lämmermann, T. & Sixt, M. Mechanical modes of ‘amoeboid’ cell migration. Curr. Opin. Cell Biol. 21, 636–644 (2009).
doi: 10.1016/j.ceb.2009.05.003
Abercrombie, M., Heaysman, J. E. & Pegrum, S. M. The locomotion of fibroblasts in culture. 3. Movements of particles on the dorsal surface of the leading lamella. Exp. Cell Res. 62, 389–398 (1970).
doi: 10.1016/0014-4827(70)90570-7
Liu, Y.-J. J. et al. Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells. Cell 160, 659–672 (2015).
doi: 10.1016/j.cell.2015.01.007
Friedl, P. & Wolf, K. Plasticity of cell migration: a multiscale tuning model. J. Cell Biol. 188, 11–19 (2010).
doi: 10.1083/jcb.200909003
Lämmermann, T. et al. Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 453, 51–55 (2008).
doi: 10.1038/nature06887
Bergert, M. et al. Force transmission during adhesion-independent migration. Nat. Cell Biol. 17, 524–529 (2015).
doi: 10.1038/ncb3134
Schmidt, S. & Friedl, P. Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms. Cell Tissue Res. 339, 83–92 (2010).
doi: 10.1007/s00441-009-0892-9
Hons, M. et al. Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nat. Immunol. 19, 606–616 (2018).
doi: 10.1038/s41590-018-0109-z
Woolf, E. et al. Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces. Nat. Immunol. 8, 1076–1085 (2007).
doi: 10.1038/ni1499
Calderwood, D. A., Campbell, I. D. & Critchley, D. R. Talins and kindlins: partners in integrin-mediated adhesion. Nat. Rev. Mol. Cell Biol. 14, 503–517 (2013).
doi: 10.1038/nrm3624
Le Berre, M., Aubertin, J. & Piel, M. Fine control of nuclear confinement identifies a threshold deformation leading to lamina rupture and induction of specific genes. Integr. Biol. (Camb.) 4, 1406–1414 (2012).
doi: 10.1039/c2ib20056b
Renkawitz, J. et al. Adaptive force transmission in amoeboid cell migration. Nat. Cell Biol. 11, 1438–1443 (2009).
doi: 10.1038/ncb1992
Renkawitz, J., Reversat, A., Leithner, A., Merrin, J. & Sixt, M. Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments. Methods Cell Biol. 147, 79–91 (2018).
doi: 10.1016/bs.mcb.2018.07.004
Vargas, P., Barbier, L., Sáez, P. J. & Piel, M. Mechanisms for fast cell migration in complex environments. Curr. Opin. Cell Biol. 48, 72–78 (2017).
doi: 10.1016/j.ceb.2017.04.007
Medeiros, N. A., Burnette, D. T. & Forscher, P. Myosin II functions in actin-bundle turnover in neuronal growth cones. Nat. Cell Biol. 8, 215–226 (2006).
doi: 10.1038/ncb1367
Henson, J. H. et al. Two components of actin-based retrograde flow in sea urchin coelomocytes. Mol. Biol. Cell 10, 4075–4090 (1999).
doi: 10.1091/mbc.10.12.4075
Cramer, L. P. Molecular mechanism of actin-dependent retrograde flow in lamellipodia of motile cells. Front. Biosci. 2, d260–d270 (1997).
doi: 10.2741/A189
Driscoll, M. K. et al. Cell shape dynamics: from waves to migration. PLoS Comput. Biol. 8, e1002392 (2012).
doi: 10.1371/journal.pcbi.1002392
Howe, J. D., Barry, N. P. & Bretscher, M. S. How do amoebae swim and crawl? PLoS One 8, e74382 (2013).
doi: 10.1371/journal.pone.0074382
Bae, A. J. & Bodenschatz, E. On the swimming of Dictyostelium amoebae. Proc. Natl Acad. Sci. USA 107, E165–E166 (2010).
doi: 10.1073/pnas.1011900107
Mandeville, J. T. H., Lawson, M. A. & Maxfield, F. R. Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. J. Leukoc. Biol. 61, 188–200 (1997).
doi: 10.1002/jlb.61.2.188
Tozluoğlu, M. et al. Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions. Nat. Cell Biol. 15, 751–762 (2013).
doi: 10.1038/ncb2775
Jankowiak, G., Peurichard, D., Reversat, A., Schmeiser, C. & Sixt, M. Modelling adhesion-independent cell migration. Math. Model. Methods Appl. Sci. 30, 513–537 (2020).
doi: 10.1142/S021820252050013X
Riedl, J. et al. Lifeact: a versatile marker to visualize F-actin. Nat. Methods 5, 605–607 (2008).
doi: 10.1038/nmeth.1220
Leithner, A. et al. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nat. Cell Biol. 18, 1253–1259 (2016).
doi: 10.1038/ncb3426
Shalem, O. et al. Genome-scale CRISPR–Cas9 knockout screening in human cells. Science 343, 84–87 (2014).
doi: 10.1126/science.1247005
Leithner, A., Merrin, J., Reversat, A. & Sixt, M. Geometrically complex microfluidic devices for the study of cell migration. Protoc. Exch. https://doi.org/10.1038/protex.2016.063 (2016).
Schwarz, J. et al. A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients. Sci. Rep. 6, 36440 (2016).
doi: 10.1038/srep36440
Sixt, M. & Lämmermann, T. in Cell Migration: Developmental Methods and Protocols (eds. Wells, C. M. & Parsons, M.) 149–165 (Humana, 2011).
Képiró, M. et al. para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor. Angew. Chem. Int. Ed. Engl. 53, 8211–8215 (2014).
doi: 10.1002/anie.201403540
Tinevez, J. Y. et al. TrackMate: an open and extensible platform for single-particle tracking. Methods 115, 80–90 (2017).
doi: 10.1016/j.ymeth.2016.09.016
Sommer, C., Straehle, C., Koethe, U. & Hamprecht, F. A. Ilastik: interactive learning and segmentation toolkit. In 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro 230–233 (IEEE, 2011).

Auteurs

Anne Reversat (A)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria. anne.reversat@gmail.com.
Institute of Translational Medicine, Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, UK. anne.reversat@gmail.com.

Florian Gaertner (F)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Jack Merrin (J)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Julian Stopp (J)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Saren Tasciyan (S)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Juan Aguilera (J)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Ingrid de Vries (I)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Robert Hauschild (R)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Miroslav Hons (M)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.
Institute of Scientific Instruments of the Czech Academy of Sciences, Brno, Czech Republic.
BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.

Matthieu Piel (M)

Institut Curie, PSL Research University, CNRS, UMR 144, Paris, France.
Institut Pierre-Gilles de Gennes, PSL Research University, Paris, France.

Andrew Callan-Jones (A)

Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS, Université Paris Diderot, Paris, France.

Raphael Voituriez (R)

Laboratoire de Physique Theorique de la Matière Condensée et Laboratoire Jean Perrin, CNRS/Université Pierre-et-Marie Curie, Paris, France.

Michael Sixt (M)

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria. sixt@ist.ac.at.

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