Control of Spinal Anesthesia-Induced Hypotension in Adults.
arterial hypotension
ondansetron
phenylephrine
spinal anesthesia
vasopressor
Journal
Local and regional anesthesia
ISSN: 1178-7112
Titre abrégé: Local Reg Anesth
Pays: New Zealand
ID NLM: 101566276
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
12
2019
accepted:
27
03
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
26
6
2020
Statut:
epublish
Résumé
Spinal anesthesia-induced hypotension (SAIH) occurs frequently, particularly in the elderly and in patients undergoing caesarean section. SAIH is caused by arterial and venous vasodilatation resulting from the sympathetic block along with a paradoxical activation of cardioinhibitory receptors. Bradycardia after spinal anesthesia (SA) must always be treated as a warning sign of an important hemodynamic compromise. Fluid preloading (before initiation of the SA) with colloids such as hydroxyethyl starch (HES) effectively reduces the incidence and severity of arterial hypotension, whereas crystalloid preloading is not indicated. Co-loading with crystalloid or colloid is as equally effective to HES preloading, provided that the speed of administration is adequate (ie, bolus over 5 to 10 minutes). Ephedrine has traditionally been considered the vasoconstrictor of choice, especially for use during SAIH associated with bradycardia. Phenylephrine, a α
Identifiants
pubmed: 32581577
doi: 10.2147/LRA.S240753
pii: 240753
pmc: PMC7276328
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
39-46Informations de copyright
© 2020 Ferré et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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