Expression Analysis of
GRHL3
PHLDA3
head and neck squamous cell carcinoma
Journal
Cancer management and research
ISSN: 1179-1322
Titre abrégé: Cancer Manag Res
Pays: New Zealand
ID NLM: 101512700
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
03
2020
accepted:
14
05
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
26
6
2020
Statut:
epublish
Résumé
Head and neck squamous cell carcinoma (HNSCC) includes a group of heterogeneous tumors with generally invasive behavior. The PI3K/AKT pathway plays an important role in the pathogenesis of HNSCC. In the current study, we investigated the expression of two negative feedback regulators of the PI3K pathway, namely While expression of The current study indicates dysregulation of regulators of PI3K pathway in HNSCC and their potential application as putative biomarkers for this cancer.
Sections du résumé
BACKGROUND
BACKGROUND
Head and neck squamous cell carcinoma (HNSCC) includes a group of heterogeneous tumors with generally invasive behavior. The PI3K/AKT pathway plays an important role in the pathogenesis of HNSCC.
METHODS
METHODS
In the current study, we investigated the expression of two negative feedback regulators of the PI3K pathway, namely
RESULTS
RESULTS
While expression of
DISCUSSION
CONCLUSIONS
The current study indicates dysregulation of regulators of PI3K pathway in HNSCC and their potential application as putative biomarkers for this cancer.
Identifiants
pubmed: 32581582
doi: 10.2147/CMAR.S252962
pii: 252962
pmc: PMC7276198
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4085-4096Informations de copyright
© 2020 Saffarzadeh et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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