Cardiovascular Implications in Idiopathic and Syndromic Obesity in Childhood: An Update.
Prader–Willi syndrome
cardiovascular disease
idiopathic obesity
metabolic syndrome
pediatric obesity
syndromic obesity
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2020
2020
Historique:
received:
24
02
2020
accepted:
28
04
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
11
5
2021
Statut:
epublish
Résumé
Childhood obesity is a modern worldwide epidemic with significant burden for health. It is a chronic metabolic disorder associated with multiple cardiovascular risk factors such as dyslipidemia, hypertension, stroke, and insulin resistance. Many obese adolescents remain obese into adulthood, with increased morbidity and mortality. As childhood obesity is a risk factor for adult obesity, the childhood obesity-related disorders account for an increased risk of cardiovascular consequences in adults, in addition to the effects already exerted by the fat mass in adulthood. Several papers have already described the cardiovascular implications of idiopathic obesity, while few data are available about syndromic obesity, due to the small sample size, not homogeneous phenotypes, and younger age at death. The aim of this mini-review is to give a comprehensive overview on knowledge about cardiovascular implications of idiopathic and syndromic obesity to allow the reader a quick comparison between them. The similarities and differences will be highlighted.
Identifiants
pubmed: 32582026
doi: 10.3389/fendo.2020.00330
pmc: PMC7296059
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
330Informations de copyright
Copyright © 2020 Delvecchio, Pastore, Valente and Giordano.
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