Lack of Association Between Genetic Variants at
ACE2
ARBs (angiotensin II receptor blockers)
COVID-19
NSAIDs (non-steroidal anti-inflammatory drugs)
PheWAS
SARS-CoV-2
TMPRSS2
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2020
2020
Historique:
received:
17
04
2020
accepted:
19
05
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
26
6
2020
Statut:
epublish
Résumé
Coronavirus disease 2019 (COVID-19) shows a wide variation in expression and severity of symptoms, from very mild or no symptoms, to flu-like symptoms, and in more severe cases, to pneumonia, acute respiratory distress syndrome, and even death. Large differences in outcome have also been observed between males and females. The causes for this variability are likely to be multifactorial, and to include genetics. The SARS-CoV-2 virus responsible for the infection depends on two human genes: the human receptor angiotensin converting enzyme 2 (
Identifiants
pubmed: 32582302
doi: 10.3389/fgene.2020.00613
pmc: PMC7295011
doi:
Types de publication
Journal Article
Langues
eng
Pagination
613Informations de copyright
Copyright © 2020 Lopera Maya, van der Graaf, Lanting, van der Geest, Fu, Swertz, Franke, Wijmenga, Deelen, Zhernakova, Sanna and Lifelines Cohort Study.
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