Not such a small diagnosis: small cell carcinoma of the prostate.
Journal
Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
06
03
2020
accepted:
09
04
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
26
6
2020
Statut:
epublish
Résumé
Small cell carcinoma (SCC) is an aggressive malignancy most commonly described in the lung. We present a case of a 61-year-old male who presented with a neck swelling and was subsequently found to have metastatic SCC of the prostate. Clinicians should be aware that it metastasizes early. Unlike conventional prostate adenocarcinoma, it is not a prostate-specific antigen (PSA) secreting tumor hence serum levels do not correlate with disease severity, and a low PSA reading may give false reassurance. In the future, further studies on genomic typing and novel targeted therapies may achieve better clinical outcomes for patients with this aggressive type of prostate cancer.
Identifiants
pubmed: 32582431
doi: 10.1093/jscr/rjaa117
pii: rjaa117
pmc: PMC7299610
doi:
Types de publication
Case Reports
Langues
eng
Pagination
rjaa117Informations de copyright
Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.
Références
Am J Surg Pathol. 2014 Jun;38(6):756-67
pubmed: 24705311
Urol Case Rep. 2017 Apr 26;13:61-62
pubmed: 28462157
Can J Neurol Sci. 2002 Nov;29(4):375-7
pubmed: 12463494
Semin Oncol. 2007 Feb;34(1):22-9
pubmed: 17270662
Nat Rev Urol. 2014 Apr;11(4):213-9
pubmed: 24535589
J Natl Cancer Inst. 1981 Sep;67(3):607-12
pubmed: 6268879
Prostate Cancer. 2011;2011:543272
pubmed: 22110988
BJU Int. 2012 Mar;109(6):824-30
pubmed: 21883857
Int J Urol. 2018 Apr;25(4):345-351
pubmed: 29396873