A Patient-Specific CFD Pipeline Using Doppler Echocardiography for Application in Coarctation of the Aorta in a Limited Resource Clinical Context.

Doppler echocardiography coarctation of the aorta computational fluid dynamics congenital heart disease patient-specific

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2020
Historique:
received: 19 12 2019
accepted: 14 04 2020
entrez: 26 6 2020
pubmed: 26 6 2020
medline: 26 6 2020
Statut: epublish

Résumé

Congenital heart disease (CHD) is the most common birth defect globally and coarctation of the aorta (CoA) is one of the commoner CHD conditions, affecting around 1/1800 live births. CoA is considered a CHD of critical severity. Unfortunately, the prognosis for a child born in a low and lower-middle income country (LLMICs) with CoA is far worse than in a high-income country. Reduced diagnostic and interventional capacities of specialists in these regions lead to delayed diagnosis and treatment, which in turn lead to more cases presenting at an advanced stage. Computational fluid dynamics (CFD) is an important tool in this context since it can provide additional diagnostic data in the form of hemodynamic parameters. It also provides an

Identifiants

pubmed: 32582648
doi: 10.3389/fbioe.2020.00409
pmc: PMC7283385
doi:

Types de publication

Journal Article

Langues

eng

Pagination

409

Subventions

Organisme : British Heart Foundation
ID : CH/13/2/30154
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P025463/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S005242/1
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/15/12/31616
Pays : United Kingdom

Informations de copyright

Copyright © 2020 Swanson, Owen, Keshmiri, Deyranlou, Aldersley, Lawrenson, Human, De Decker, Fourie, Comitis, Engel, Keavney, Zühlke, Ngoepe and Revell.

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Auteurs

Liam Swanson (L)

Department of Mechanical Engineering, University of Cape Town, Cape Town, South Africa.

Benjamin Owen (B)

Department of Mechanical, Aerospace and Civil Engineering (MACE), The University of Manchester, Manchester, United Kingdom.

Amir Keshmiri (A)

Department of Mechanical, Aerospace and Civil Engineering (MACE), The University of Manchester, Manchester, United Kingdom.

Amin Deyranlou (A)

Department of Mechanical, Aerospace and Civil Engineering (MACE), The University of Manchester, Manchester, United Kingdom.

Thomas Aldersley (T)

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

John Lawrenson (J)

Department of Paediatrics and Child Health, Tygerberg Hospital, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

Paul Human (P)

Christiaan Barnard Division of Cardiothoracic Surgery, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.

Rik De Decker (R)

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

Barend Fourie (B)

Department of Paediatrics and Child Health, Tygerberg Hospital, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

George Comitis (G)

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

Mark E Engel (ME)

Department of Medicine, University of Cape Town, Cape Town, South Africa.

Bernard Keavney (B)

Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, School of Medical Sciences, The University of Manchester, Manchester, United Kingdom.
Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.

Liesl Zühlke (L)

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

Malebogo Ngoepe (M)

Department of Mechanical Engineering, University of Cape Town, Cape Town, South Africa.

Alistair Revell (A)

Department of Mechanical, Aerospace and Civil Engineering (MACE), The University of Manchester, Manchester, United Kingdom.

Classifications MeSH