Synthesized Geopolymers Adsorb Bacterial Proteins, Toxins, and Cells.
adsorbent
adsorption
aluminosilicate
bacteria
geopolymer
nanoporous
toxin removal
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
01
2020
accepted:
04
05
2020
entrez:
26
6
2020
pubmed:
26
6
2020
medline:
26
6
2020
Statut:
epublish
Résumé
Pore-forming and hemolytic toxins are bacterial cytotoxic proteins required for virulence in many pathogens, including staphylococci and streptococci, and are notably associated with clinical manifestations of disease. Inspired by adsorption properties of naturally occurring aluminosilicates, we engineered inexpensive, laboratory-synthesized, aluminosilicate geopolymers with controllable pore and surface characteristics to remove pathogenic or cytotoxic material from the surrounding environment. In this study, macroporous and mesoporous geopolymers were produced with and without stearic acid surface modifications. Geopolymer binding efficacies were assessed by measuring adsorption of methicillin-resistant
Identifiants
pubmed: 32582660
doi: 10.3389/fbioe.2020.00527
pmc: PMC7283576
doi:
Types de publication
Journal Article
Langues
eng
Pagination
527Subventions
Organisme : NIAID NIH HHS
ID : R21 AI121733
Pays : United States
Informations de copyright
Copyright © 2020 Popovich, Chen, Iannuzo, Ganser, Seo and Haydel.
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