Atopic dermatitis severity during exposure to air pollutants and weather changes with an Artificial Neural Network (ANN) analysis.
air pollution
atopic dermatitis
climate change
weather
Journal
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
ISSN: 1399-3038
Titre abrégé: Pediatr Allergy Immunol
Pays: England
ID NLM: 9106718
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
26
03
2020
revised:
06
06
2020
accepted:
16
06
2020
pubmed:
26
6
2020
medline:
19
8
2021
entrez:
26
6
2020
Statut:
ppublish
Résumé
Epidemiological studies have shown an association between global warming, air pollution, and allergic diseases. Several air pollutants, including volatile organic compounds, formaldehyde, toluene, nitrogen dioxide (NO Sixty AD patients ≥5 years of age (mean age: 23.5 ± 12.5 years), living in the Campania Region (Southern Italy), were followed for 18 months. The primary outcome was the effect of atmospheric and climatic factors on signs and symptoms of AD, assessed using the SCORAD (SCORing Atopic Dermatitis) index. We measured mean daily temperature (TOD), outdoor relative humidity (RH), diurnal temperature range (DTR), precipitation, particulate with aerodynamic diameter ≤ 10 μm (PM The severity of AD symptoms was positively correlated with outdoor temperatures (TOD, DTR), RH, precipitation, PM The results of the present study provide evidence that weather changes and air pollutions have a significant impact on skin reactivity and symptoms in AD patients, increasing the severity of the dermatitis. The knowledge of the single variables proportion on AD severity symptoms is important to propose alerts for exacerbations in patients with AD of each age. This finding represents a good starting point for further future research in an area of increasingly growing interest.
Sections du résumé
BACKGROUND
Epidemiological studies have shown an association between global warming, air pollution, and allergic diseases. Several air pollutants, including volatile organic compounds, formaldehyde, toluene, nitrogen dioxide (NO
MATERIALS AND METHODS
Sixty AD patients ≥5 years of age (mean age: 23.5 ± 12.5 years), living in the Campania Region (Southern Italy), were followed for 18 months. The primary outcome was the effect of atmospheric and climatic factors on signs and symptoms of AD, assessed using the SCORAD (SCORing Atopic Dermatitis) index. We measured mean daily temperature (TOD), outdoor relative humidity (RH), diurnal temperature range (DTR), precipitation, particulate with aerodynamic diameter ≤ 10 μm (PM
RESULTS
The severity of AD symptoms was positively correlated with outdoor temperatures (TOD, DTR), RH, precipitation, PM
CONCLUSION
The results of the present study provide evidence that weather changes and air pollutions have a significant impact on skin reactivity and symptoms in AD patients, increasing the severity of the dermatitis. The knowledge of the single variables proportion on AD severity symptoms is important to propose alerts for exacerbations in patients with AD of each age. This finding represents a good starting point for further future research in an area of increasingly growing interest.
Substances chimiques
Air Pollutants
0
Particulate Matter
0
Ozone
66H7ZZK23N
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
938-945Informations de copyright
© 2020 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
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