Listed for sale: Analyzing data on fentanyl, fentanyl analogs and other novel synthetic opioids on one cryptomarket.
Cryptomarkets
Darknet markets
Fentanyl
Fentanyl analogs
Synthetic opioids
Journal
Drug and alcohol dependence
ISSN: 1879-0046
Titre abrégé: Drug Alcohol Depend
Pays: Ireland
ID NLM: 7513587
Informations de publication
Date de publication:
01 Aug 2020
01 Aug 2020
Historique:
received:
12
02
2020
revised:
14
05
2020
accepted:
08
06
2020
medline:
26
6
2020
pubmed:
26
6
2020
entrez:
26
6
2020
Statut:
ppublish
Résumé
The United States is facing a "triple wave" epidemic fueled by novel synthetic opioids. Cryptomarkets, anonymous marketplaces located on the deep web, play an increasingly important role in the distribution of illicit substances. This article presents the data collected and processed by the eDarkTrends platform concerning the availability trends of novel synthetic opioids listed on one cryptomarket. Listings from the DreamMarket cryptomarket "Opioids" and "Research Chemicals" sections were collected between March 2018 and January 2019. Collected data were processed using eDarkTrends Named Entity Recognition algorithm to identify opioid drugs, and to analyze their availability trends in terms of frequency of listings, available average weights, average prices, and geographic indicators of shipment origin and destination information. 95,011 opioid-related listings were collected through 26 crawling sessions. 33 novel synthetic opioids were identified in 3.3 % of the collected listings. 44.7 % of these listings advertised fentanyl (pharmaceutical and non-pharmaceutical) or fentanyl analogs for an average of 2.8 kgs per crawl. "Synthetic heroin" accounted for 33.2 % of novel synthetic opioid listings for an average 1.1 kgs per crawl with 97.7 % of listings advertised as shipped from Canada. Other novel synthetic opioids (e.g., U-47,700, AP-237) represented 22 % of these listings for an average of 6.1 kgs per crawl with 97.2 % of listings advertised as shipped from China. Our data indicate consistent availability of a wide variety of novel synthetic opioids both in retail and wholesale-level amounts. Identification of new substances highlights the value of cryptomarket data for early warning systems of emerging substance use trends.
Sections du résumé
BACKGROUND
BACKGROUND
The United States is facing a "triple wave" epidemic fueled by novel synthetic opioids. Cryptomarkets, anonymous marketplaces located on the deep web, play an increasingly important role in the distribution of illicit substances. This article presents the data collected and processed by the eDarkTrends platform concerning the availability trends of novel synthetic opioids listed on one cryptomarket.
METHODS
METHODS
Listings from the DreamMarket cryptomarket "Opioids" and "Research Chemicals" sections were collected between March 2018 and January 2019. Collected data were processed using eDarkTrends Named Entity Recognition algorithm to identify opioid drugs, and to analyze their availability trends in terms of frequency of listings, available average weights, average prices, and geographic indicators of shipment origin and destination information.
RESULTS
RESULTS
95,011 opioid-related listings were collected through 26 crawling sessions. 33 novel synthetic opioids were identified in 3.3 % of the collected listings. 44.7 % of these listings advertised fentanyl (pharmaceutical and non-pharmaceutical) or fentanyl analogs for an average of 2.8 kgs per crawl. "Synthetic heroin" accounted for 33.2 % of novel synthetic opioid listings for an average 1.1 kgs per crawl with 97.7 % of listings advertised as shipped from Canada. Other novel synthetic opioids (e.g., U-47,700, AP-237) represented 22 % of these listings for an average of 6.1 kgs per crawl with 97.2 % of listings advertised as shipped from China.
CONCLUSIONS
CONCLUSIONS
Our data indicate consistent availability of a wide variety of novel synthetic opioids both in retail and wholesale-level amounts. Identification of new substances highlights the value of cryptomarket data for early warning systems of emerging substance use trends.
Identifiants
pubmed: 32585419
pii: S0376-8716(20)30280-5
doi: 10.1016/j.drugalcdep.2020.108115
pmc: PMC7736148
mid: NIHMS1603615
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108115Subventions
Organisme : NIMH NIH HHS
ID : R01 MH105384
Pays : United States
Organisme : NIDA NIH HHS
ID : R21 DA044518
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No conflict declared.
Références
MMWR Morb Mortal Wkly Rep. 2016 Jan 01;64(50-51):1378-82
pubmed: 26720857
JAMA. 2018 May 1;319(17):1819-1821
pubmed: 29715347
Int J Drug Policy. 2016 Sep;35:7-15
pubmed: 27260863
MMWR Morb Mortal Wkly Rep. 2018 Jan 04;67(5152):1419-1427
pubmed: 30605448
JAMA. 2008 Dec 10;300(22):2613-20
pubmed: 19066381
J Stud Alcohol Drugs. 2017 Nov;78(6):910-915
pubmed: 29087826
Am J Public Health. 2009 Feb;99(2):221-7
pubmed: 18799767
Comput Math Organ Theory. 2019 Mar;25(1):48-59
pubmed: 32577089
Int J Drug Policy. 2019 Sep;71:183-188
pubmed: 30718120
Ann Emerg Med. 1991 Feb;20(2):158-64
pubmed: 1996799
J Biomed Inform. 2013 Dec;46(6):985-97
pubmed: 23892295
Int J Drug Policy. 2016 Sep;35:50-7
pubmed: 27157539
Drug Alcohol Depend. 2006 Jun;83 Suppl 1:S4-7
pubmed: 16563663
Drug Alcohol Depend. 2019 May 1;198:116-120
pubmed: 30909018
Drug Alcohol Depend. 2020 Mar 1;208:107779
pubmed: 31931266
Am J Addict. 2015 Aug;24(5):403-9
pubmed: 26009867
Int J Drug Policy. 2014 Mar;25(2):257-66
pubmed: 24238956
MMWR Morb Mortal Wkly Rep. 2017 Sep 01;66(34):904-908
pubmed: 28859050
Int J Drug Policy. 2016 Sep;35:1-6
pubmed: 27523571
AI Matters. 2015 Jun;1(4):4-12
pubmed: 27239556
Int J Drug Policy. 2016 Sep;35:16-23
pubmed: 27520115
PLoS One. 2013;8(2):e54496
pubmed: 23405084
Int J Drug Policy. 2015 Nov;26(11):1113-23
pubmed: 25681266
J Anal Toxicol. 2016 Nov;40(9):709-717
pubmed: 27590036
Neuropharmacology. 2018 May 15;134(Pt A):101-107
pubmed: 28807672
Pharmacoepidemiol Drug Saf. 2006 Sep;15(9):618-27
pubmed: 16862602
CJEM. 2019 Mar;21(2):175-176
pubmed: 30404669
MMWR Morb Mortal Wkly Rep. 2016 Aug 26;65(33):844-9
pubmed: 27560948
Int J Drug Policy. 2017 Aug;46:146-155
pubmed: 28735775
Addiction. 2014 Nov;109(11):1889-98
pubmed: 24938727
JAMA Psychiatry. 2014 Jul 1;71(7):821-6
pubmed: 24871348
J Psychoactive Drugs. 2016 Nov-Dec;48(5):321-329
pubmed: 27660913
Epidemiology. 2019 Mar;30(2):212-220
pubmed: 30721165
Drug Alcohol Depend. 2016 Mar 1;160:127-34
pubmed: 26785634
Int J Drug Policy. 2017 Jun;44:121-129
pubmed: 28578250