Discovery of Novel Recurrent Mutations and Clinically Meaningful Subgroups in Nodal Marginal Zone Lymphoma.

RNA sequencing genetics malignant lymphoma marginal zone lymphoma whole exome sequencing

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
23 Jun 2020
Historique:
received: 19 05 2020
revised: 11 06 2020
accepted: 18 06 2020
entrez: 27 6 2020
pubmed: 27 6 2020
medline: 27 6 2020
Statut: epublish

Résumé

Nodal marginal zone lymphoma (NMZL) is a rare B-cell neoplasm, the genetic and transcriptomic landscape of which are unclear. Using high-throughput sequencing for whole-exome and transcriptome, we investigated the genetic characteristics of NMZL in a discovery cohort (

Identifiants

pubmed: 32585984
pii: cancers12061669
doi: 10.3390/cancers12061669
pmc: PMC7352856
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Seoul National University (SNU) Invitation Program for Distinguished Scholar
ID : 0320170160 [2017-1312]
Organisme : Ministry of Education, Science and Technology
ID : NRF-2016R1D1A1B01015964
Organisme : Ministry of Education, Science and Technology
ID : NRF-2019R1F1A1061920

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Auteurs

Jiwon Koh (J)

Department of Pathology, Seoul National University Hospital, Seoul 03080, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.

Insoon Jang (I)

Division of Clinical Bioinformatics, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.

Seongmin Choi (S)

Division of Clinical Bioinformatics, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.
Seoul National University College of Medicine, Seoul 03080, Korea.

Sehui Kim (S)

Department of Pathology, Seoul National University Hospital, Seoul 03080, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.

Ingeon Jang (I)

Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.

Hyun Kyung Ahn (HK)

Cancer Research Institute, Seoul National University, Seoul 03080, Korea.

Cheol Lee (C)

Department of Pathology, Seoul National University Hospital, Seoul 03080, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.

Jin Ho Paik (JH)

Department of Pathology, Seoul National University Bundang Hospital, Seongnam-si 46371, Korea.

Chul Woo Kim (CW)

Department of Pathology, Seoul National University Hospital, Seoul 03080, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.

Megan S Lim (MS)

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

Kwangsoo Kim (K)

Division of Clinical Bioinformatics, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Korea.

Yoon Kyung Jeon (YK)

Department of Pathology, Seoul National University Hospital, Seoul 03080, Korea.
Department of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
Cancer Research Institute, Seoul National University, Seoul 03080, Korea.

Classifications MeSH