Changes in the Intestinal Microbiome during a Multispecies Probiotic Intervention in Compensated Cirrhosis.
16S
RNA
cirrhosis
gastrointestinal microbiome
probiotics
ribosomal
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
23 Jun 2020
23 Jun 2020
Historique:
received:
29
05
2020
revised:
17
06
2020
accepted:
19
06
2020
entrez:
27
6
2020
pubmed:
27
6
2020
medline:
27
2
2021
Statut:
epublish
Résumé
Probiotics have been used in trials to therapeutically modulate the gut microbiome and have shown beneficial effects in cirrhosis. However, their effect on the microbiome of cirrhosis patients is not fully understood yet. Here, we tested the effects of a multispecies probiotic on microbiome composition in compensated cirrhosis. The gut microbiome composition of 58 patients with compensated cirrhosis from a randomized controlled trial who received a daily dose of multispecies probiotics or placebo for six months was analysed by 16S rRNA gene sequencing. Microbiome composition of patients who received probiotics was enriched with probiotic strains and the abundance of
Identifiants
pubmed: 32585997
pii: nu12061874
doi: 10.3390/nu12061874
pmc: PMC7353185
pii:
doi:
Substances chimiques
RNA, Ribosomal, 16S
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Austrian Science Fund
ID : P24362
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