Unmasking the Many Faces of Giloy (Tinospora cordifolia L.): A Fresh Look on its Phytochemical and Medicinal Properties.


Journal

Current pharmaceutical design
ISSN: 1873-4286
Titre abrégé: Curr Pharm Des
Pays: United Arab Emirates
ID NLM: 9602487

Informations de publication

Date de publication:
Historique:
received: 17 02 2020
accepted: 26 05 2020
pubmed: 27 6 2020
medline: 25 2 2023
entrez: 27 6 2020
Statut: ppublish

Résumé

Plants have been used to treat health disorders and prevent diseases since antiquity in all civilizations including the Indian and Chinse. Giloy (Tinospora cordifolia L.) is one of the most important medicinal plants in Indian folk medicine and is commonly known as the "Heart-leaved Moonseed" or "Guduchi". Giloy is a perennial shrubby creeper of the Menispermaceae family. It is native to the tropical areas of India, Sri Lanka, Myanmar, Sothern Eastern Asia, Africa, and Australia. It attracted attention in the last few decades because its roots, stems, and leaves are used in folk medicine treating several disorders. To reveal its potential, we reviewed the literature on this plant over the last five decades using several search engines. Giloy is recommended in diabetes, stomachache, jaundice, urinary problems, skin ailments, and prolonged diarrhea and dysentery. The medicinal properties of T. cordifolia extracts were attributed to its phytochemical content including steroids, alkaloids, diterpenoid lactones, and glycosides. In this review, we summarized the phytochemical content of T. cordifolia and its medicinal properties with special emphasis on its antioxidant, anti-inflammatory, and cytotoxic activities. We aimed to provide natural product researchers with a full picture of the potential applications of this plant in the development of food additives and nutraceuticals.

Sections du résumé

BACKGROUND BACKGROUND
Plants have been used to treat health disorders and prevent diseases since antiquity in all civilizations including the Indian and Chinse. Giloy (Tinospora cordifolia L.) is one of the most important medicinal plants in Indian folk medicine and is commonly known as the "Heart-leaved Moonseed" or "Guduchi". Giloy is a perennial shrubby creeper of the Menispermaceae family. It is native to the tropical areas of India, Sri Lanka, Myanmar, Sothern Eastern Asia, Africa, and Australia. It attracted attention in the last few decades because its roots, stems, and leaves are used in folk medicine treating several disorders.
METHODS METHODS
To reveal its potential, we reviewed the literature on this plant over the last five decades using several search engines.
RESULTS RESULTS
Giloy is recommended in diabetes, stomachache, jaundice, urinary problems, skin ailments, and prolonged diarrhea and dysentery. The medicinal properties of T. cordifolia extracts were attributed to its phytochemical content including steroids, alkaloids, diterpenoid lactones, and glycosides.
CONCLUSION CONCLUSIONS
In this review, we summarized the phytochemical content of T. cordifolia and its medicinal properties with special emphasis on its antioxidant, anti-inflammatory, and cytotoxic activities. We aimed to provide natural product researchers with a full picture of the potential applications of this plant in the development of food additives and nutraceuticals.

Identifiants

pubmed: 32586250
pii: CPD-EPUB-107638
doi: 10.2174/1381612826666200625111530
doi:

Substances chimiques

Phytochemicals 0
Plant Extracts 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2571-2581

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Deepak Kumar Verma (DK)

Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur - 721302, West Bengal, India.

Kimmy G (K)

Department of Food Engineering and Technology, Sant Longowal Institute of Engineering and Technology Longowal, Sangrur - 148106, Punjab, India.

Pradyuman Kumar (P)

Department of Food Engineering and Technology, Sant Longowal Institute of Engineering and Technology Longowal, Sangrur - 148106, Punjab, India.

Mohamed El-Shazly (M)

Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street, Abassia, Cairo 11566, Egypt.

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