Brachytherapy for meningiomas.
Brachytherapy
High-grade
I-125
Iodine-125
Meningioma
Recurrent
Journal
Handbook of clinical neurology
ISSN: 0072-9752
Titre abrégé: Handb Clin Neurol
Pays: Netherlands
ID NLM: 0166161
Informations de publication
Date de publication:
2020
2020
Historique:
entrez:
27
6
2020
pubmed:
27
6
2020
medline:
14
4
2021
Statut:
ppublish
Résumé
Interstitial intracranial radiotherapy implants, or brachytherapy, is an adjuvant option for treatment of recurrent high-grade meningiomas after resection. The implants are placed in the resection cavity following tumor resection. The most commonly used isotope is Iodine-125 (I-125). While there are no controlled studies comparing treatment of meningiomas with or without brachytherapy, several case series report good long-term survival, suggesting that this may be a useful adjuvant for recurrent high-grade tumors. Complications can occur including radiation necrosis, impaired wound healing, hydrocephalus and infection. In the future, new isotopes are being explored that may have fewer complications and better safety profiles.
Identifiants
pubmed: 32586503
pii: B978-0-12-822198-3.00049-5
doi: 10.1016/B978-0-12-822198-3.00049-5
pii:
doi:
Substances chimiques
Iodine Radioisotopes
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
303-307Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.