Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise.
Acute aerobic exercise
aging
insulin growth factor-1 signaling
microRNA profiling
plasma exosomes
regular endurance training
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
03
2020
accepted:
14
05
2020
entrez:
27
6
2020
pubmed:
27
6
2020
medline:
27
6
2020
Statut:
epublish
Résumé
Exercise has multi-systemic benefits and attenuates the physiological impairments associated with aging. Emerging evidence suggests that circulating exosomes mediate some of the beneficial effects of exercise via the transfer of microRNAs between tissues. However, the impact of regular exercise and acute exercise on circulating exosomal microRNAs (exomiRs) in older populations remains unknown. In the present study, we analyzed circulating exomiR expression in endurance-trained elderly men (
Identifiants
pubmed: 32587527
doi: 10.3389/fphys.2020.00605
pmc: PMC7298138
doi:
Types de publication
Journal Article
Langues
eng
Pagination
605Subventions
Organisme : NIA NIH HHS
ID : K01 AG044437
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK020541
Pays : United States
Organisme : NIDDK NIH HHS
ID : U24 DK112331
Pays : United States
Informations de copyright
Copyright © 2020 Nair, Ge, Li, Pincas, Jain, Seenarine, Amper, Goodpaster, Walsh, Coen and Sealfon.
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