Validation of the Neuropsychiatric Inventory Based on Item Response Theory.
Factor analysis
Neuropsychiatric inventory
item characteristic curves
item response theory
Journal
Journal of Alzheimer's disease reports
ISSN: 2542-4823
Titre abrégé: J Alzheimers Dis Rep
Pays: Netherlands
ID NLM: 101705500
Informations de publication
Date de publication:
20 May 2020
20 May 2020
Historique:
entrez:
27
6
2020
pubmed:
27
6
2020
medline:
27
6
2020
Statut:
epublish
Résumé
The Neuropsychiatric Inventory (NPI) is a widely used scale for the assessment of the behavioral and psychological symptoms of dementia (BPSD). We previously developed a novel dementia scale, the ABC dementia scale, in the TRIAD1412 trial and we compared the BPSD domain scores with the NPI scores. We, therefore, considered that we should investigate the quality of the NPI items using statistical approaches. We investigated the statistical characteristics of the 12 questions or items in the Japanese version of the NPI using the item response theory. This theory is the standard approach for the development of a new assessment scale and we used it to evaluate the quality of the items in the NPI. First, we performed factor analysis with Promax rotation to identify latent constructs in the data from 312 patients obtained in TRIAD1412. Second, following the result of the factor analysis, we divided the 12 items into domains and then investigated the characteristics of the sub-syndromes in each domain using item response category characteristic curves. We found three latent constructs or domains: "hyperactivity," "psychosis and apathy," and "affect" (Cronbach's The NPI item characteristics indicate that while the scale can distinguish whether patients have severe BPSD or not, it cannot estimate the degree of severity in a suspected case with a mild or unknown level of BPSD.
Sections du résumé
BACKGROUND
BACKGROUND
The Neuropsychiatric Inventory (NPI) is a widely used scale for the assessment of the behavioral and psychological symptoms of dementia (BPSD). We previously developed a novel dementia scale, the ABC dementia scale, in the TRIAD1412 trial and we compared the BPSD domain scores with the NPI scores. We, therefore, considered that we should investigate the quality of the NPI items using statistical approaches.
OBJECTIVE
OBJECTIVE
We investigated the statistical characteristics of the 12 questions or items in the Japanese version of the NPI using the item response theory. This theory is the standard approach for the development of a new assessment scale and we used it to evaluate the quality of the items in the NPI.
METHODS
METHODS
First, we performed factor analysis with Promax rotation to identify latent constructs in the data from 312 patients obtained in TRIAD1412. Second, following the result of the factor analysis, we divided the 12 items into domains and then investigated the characteristics of the sub-syndromes in each domain using item response category characteristic curves.
RESULTS
RESULTS
We found three latent constructs or domains: "hyperactivity," "psychosis and apathy," and "affect" (Cronbach's
CONCLUSION
CONCLUSIONS
The NPI item characteristics indicate that while the scale can distinguish whether patients have severe BPSD or not, it cannot estimate the degree of severity in a suspected case with a mild or unknown level of BPSD.
Identifiants
pubmed: 32587948
doi: 10.3233/ADR-200172
pii: ADR200172
pmc: PMC7306920
doi:
Types de publication
Journal Article
Langues
eng
Pagination
151-159Informations de copyright
© 2020 – IOS Press and the authors. All rights reserved.
Déclaration de conflit d'intérêts
The authors have no conflict of interest to report.
Références
Int Psychogeriatr. 1992;4 Suppl 2:161-84
pubmed: 1288661
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
Dement Geriatr Cogn Disord. 1999 Mar-Apr;10(2):130-8
pubmed: 10026387
No To Shinkei. 2006 Sep;58(9):785-90
pubmed: 17052006
Dement Geriatr Cogn Dis Extra. 2018 Mar 14;8(1):85-97
pubmed: 29706985
Alzheimer Dis Assoc Disord. 2001 Apr-Jun;15(2):89-95
pubmed: 11391090
Int J Geriatr Psychiatry. 2005 Feb;20(2):137-45
pubmed: 15660411
Nord J Psychiatry. 2008;62(6):481-5
pubmed: 19031152
Patient. 2014;7(1):23-35
pubmed: 24403095
J Neurol Neurosurg Psychiatry. 2005 Oct;76(10):1337-41
pubmed: 16170072
Neurology. 1984 Jul;34(7):939-44
pubmed: 6610841
Dement Geriatr Cogn Disord. 2003;15(2):99-105
pubmed: 12566599
Rev Med Interne. 2003 Oct;24 Suppl 3:319s-324s
pubmed: 14710451
Alzheimers Dement. 2011 May;7(3):263-9
pubmed: 21514250
Clin Interv Aging. 2014 Jul 08;9:1051-61
pubmed: 25031530
Alzheimers Dement. 2011 May;7(3):270-9
pubmed: 21514249
Aging (Milano). 2001 Jun;13(3):240-6
pubmed: 11444257
Int Psychogeriatr. 2004 Sep;16(3):295-315
pubmed: 15559754
Br J Psychiatry. 1982 Jun;140:566-72
pubmed: 7104545
J Am Geriatr Soc. 1998 Feb;46(2):210-5
pubmed: 9475452
Neurology. 1994 Dec;44(12):2308-14
pubmed: 7991117
Int J Geriatr Psychiatry. 2004 Nov;19(11):1035-9
pubmed: 15481075
Int J Geriatr Psychiatry. 1997 Nov;12(11):1074-8
pubmed: 9427091