Nutritional management of lactose intolerance: the importance of diet and food labelling.

Food hidden lactose Lactose food content Lactose intolerance Lactose intolerance management Lactose-free labelling Nutritional approach Nutritional deficiency

Journal

Journal of translational medicine
ISSN: 1479-5876
Titre abrégé: J Transl Med
Pays: England
ID NLM: 101190741

Informations de publication

Date de publication:
26 06 2020
Historique:
received: 09 05 2020
accepted: 18 06 2020
entrez: 28 6 2020
pubmed: 28 6 2020
medline: 15 5 2021
Statut: epublish

Résumé

Worldwide, 70% of the adult population has limited expression of lactase enzyme with a wide variation among different regions and countries. Lactase deficiency may lead to lactose intolerance (LI). Depending both on the amount of lactose ingested and on the lactase activity, people who suffer from lactose malabsorption might experience numerous gastrointestinal and extra-intestinal symptoms and manifestations. Treatment of LI mainly consists of reducing or eliminating lactose from the diet until the symptoms disappear as well as supplementing lactase, and inducing colon microbiome adaptation by probiotics. Cow's milk is one of the major source of calcium and several other vitamins and minerals. Thus, a complete exclusion of dairy products may favor the development of bone diseases such as osteopenia and osteoporosis. Therefore, the dietetic approach has a crucial role in the management of LI patients. Additionally, the use of lactose and milk-derived products in non-dairy products (e.g., baked goods, breakfast cereals, drinks, and processed meat) has become widespread in the modern industry (the so-called "hidden lactose"). In this regard, a strict adherence to the lactose-free diet becomes challenging for LI patients, forced to continuous check of all products and food labels. In fact, lactose-free product labeling is still controversial. Considering that nowadays a specific cut-off value establishing "lactose-free" labeling policy is lacking and that there is no universal law regulating the production and commercialization of "delactosed" products, identification of specific safe and suitable products with a well-recognized lactose-free logo might help consumers. This narrative review aims to identify the dietary management for lactose intolerant people, avoiding symptoms and nutrients deficiencies, helped by the use of specific labelling to guide them to choose the safer product on the market.

Identifiants

pubmed: 32590986
doi: 10.1186/s12967-020-02429-2
pii: 10.1186/s12967-020-02429-2
pmc: PMC7318541
doi:

Substances chimiques

Lactase EC 3.2.1.108
Lactose J2B2A4N98G

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

260

Références

Am J Clin Nutr. 2014 May;99(5 Suppl):1217S-22S
pubmed: 24646824
Food Res Int. 2016 Nov;89(Pt 1):514-525
pubmed: 28460946
Am J Clin Nutr. 1991 Dec;54(6):1041-6
pubmed: 1957819
Ann Intern Med. 2010 Jun 15;152(12):797-803
pubmed: 20404262
Pediatrics. 2006 Sep;118(3):1279-86
pubmed: 16951027
Animals (Basel). 2019 Dec 17;9(12):
pubmed: 31861194
Nutrients. 2018 Nov 01;10(11):
pubmed: 30388735
Lancet Gastroenterol Hepatol. 2017 Oct;2(10):738-746
pubmed: 28690131
Adv Nutr. 2015 May 15;6(3):245-59
pubmed: 25979490
Crit Rev Food Sci Nutr. 2015;55(3):291-303
pubmed: 24915389
Curr Gastroenterol Rep. 2017 May;19(5):23
pubmed: 28421381
J Pediatr Gastroenterol Nutr. 2017 May;64(5):799-805
pubmed: 27540708
J Clin Endocrinol Metab. 2011 Jan;96(1):53-8
pubmed: 21118827
Pediatrics. 2007 Sep;120(3):e669-77
pubmed: 17766507
J Neurogastroenterol Motil. 2011 Jul;17(3):312-7
pubmed: 21860825
Nutrients. 2019 Mar 05;11(3):
pubmed: 30841534
Am J Clin Nutr. 2019 Aug 1;110(2):273-279
pubmed: 31175813
Nutrients. 2015 Aug 31;7(9):7312-31
pubmed: 26404364
Pediatrics. 2006 Feb;117(2):578-85
pubmed: 16452385
J Public Health Res. 2016 Dec 21;5(3):768
pubmed: 28083524
Econ Hum Biol. 2012 Jul;10(3):299-309
pubmed: 21890437
Annu Rev Genet. 2003;37:197-219
pubmed: 14616060
Am J Clin Nutr. 2017 Aug;106(2):597-602
pubmed: 28592600
Bone. 2008 Aug;43(2):312-21
pubmed: 18539555
J Am Coll Nutr. 2003 Jun;22(3):201-7
pubmed: 12805246
Clin Exp Gastroenterol. 2018 Jun 18;11:243-248
pubmed: 29950879
Nutrients. 2018 Dec 15;10(12):
pubmed: 30558337
Am J Clin Nutr. 2011 Jul;94(1):191-8
pubmed: 21525197
Nutr Rev. 2018 Dec 1;76(Suppl 1):4-15
pubmed: 30452699
Nutrients. 2018 Nov 02;10(11):
pubmed: 30400146
Nutrients. 2019 Jun 07;11(6):
pubmed: 31181664
N Engl J Med. 1984 Jan 5;310(1):1-3
pubmed: 6417539
Gastroenterol Res Pract. 2014;2014:464382
pubmed: 24829570
J Am Coll Nutr. 2002 Feb;21(1):47-54
pubmed: 11838887
Am J Gastroenterol. 2017 May;112(5):775-784
pubmed: 28323273
Nutrients. 2019 Mar 28;11(4):
pubmed: 30925689
Appl Physiol Nutr Metab. 2013 Aug;38(8):830-5
pubmed: 23855270
J Food Sci Technol. 2016 Sep;53(9):3408-3423
pubmed: 27777447
J Am Coll Nutr. 2000 Apr;19(2 Suppl):83S-99S
pubmed: 10759135
Food Chem. 2017 Apr 1;220:18-24
pubmed: 27855887
United European Gastroenterol J. 2013 Jun;1(3):151-9
pubmed: 24917953
Gut. 2019 Nov;68(11):2080-2091
pubmed: 31427404
Crit Rev Food Sci Nutr. 2019;59(11):1675-1683
pubmed: 29425071
Nutrients. 2019 Jun 20;11(6):
pubmed: 31226742
J Dairy Sci. 2018 Oct;101(10):8619-8640
pubmed: 30139623
J Am Coll Nutr. 2000 Apr;19(2 Suppl):147S-164S
pubmed: 10759140
Am J Clin Nutr. 2014 May;99(5 Suppl):1251S-5S
pubmed: 24695892
Int J Obes (Lond). 2014 Jul;38 Suppl 1:S25-33
pubmed: 25033961
Metabolism. 1993 Dec;42(12):1560-7
pubmed: 8246770
Nutrients. 2018 May 01;10(5):
pubmed: 29723971
J Fam Pract. 2005 Jul;54(7):613-20
pubmed: 16009090
J Bone Miner Res. 1995 Dec;10(12):2017-22
pubmed: 8619384

Auteurs

Maria Sole Facioni (MS)

AILI - Associazione Italiana Latto-Intolleranti Onlus, Lucca, Italy.

Benedetta Raspini (B)

Dietetics and Clinical Nutrition Laboratory, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

Francesca Pivari (F)

Biochemistry and Molecular Biology Laboratory, Department of Health Sciences, University of Milan, Milan, Italy. francesca.pivari@unimi.it.

Elena Dogliotti (E)

Fondazione Umberto Veronesi, Milan, Italy.

Hellas Cena (H)

Dietetics and Clinical Nutrition Laboratory, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Clinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, Pavia, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH