Toxic effect and genotoxicity of carvacrol ethers in Drosophila melanogaster.


Journal

Mutation research
ISSN: 1873-135X
Titre abrégé: Mutat Res
Pays: Netherlands
ID NLM: 0400763

Informations de publication

Date de publication:
Historique:
received: 21 04 2020
revised: 26 05 2020
accepted: 16 06 2020
pubmed: 28 6 2020
medline: 15 12 2020
entrez: 28 6 2020
Statut: ppublish

Résumé

The present study investigated the effect of four carvacrol ethers (propyl-, butyl, octyl- and benzyl) on the viability, level of dominant lethal mutations of Drosophila melanogaster and their influence on the multiplication of the nuclear genome in salivary gland cells. The fertility and viability of fruit flies were assessed after oral administration (0.05 % to culture medium) and inhalation exposure (5 mg per 1 cm

Identifiants

pubmed: 32593030
pii: S0027-5107(20)30046-4
doi: 10.1016/j.mrfmmm.2020.111713
pii:
doi:

Substances chimiques

Cymenes 0
Ethers 0
carvacrol 9B1J4V995Q

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111713

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Mariia Nesterkina (M)

Department of Organic and Pharmaceutical Technologies, Odessa National Polytechnic University, Odessa, 65044, Ukraine. Electronic address: m.v.nesterkina@opu.ua.

Svitlana Bilokon (S)

Department of Genetics and Molecular Biology, Odessa I.I. Mechnikov National University, Odessa, 65082, Ukraine.

Tetiana Alieksieieva (T)

Department of Genetics and Molecular Biology, Odessa I.I. Mechnikov National University, Odessa, 65082, Ukraine.

Sabina Chebotar (S)

Department of Genetics and Molecular Biology, Odessa I.I. Mechnikov National University, Odessa, 65082, Ukraine.

Iryna Kravchenko (I)

Department of Organic and Pharmaceutical Technologies, Odessa National Polytechnic University, Odessa, 65044, Ukraine.

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Classifications MeSH