Malocclusion traits and oral health-related quality of life in children with osteogenesis imperfecta: A cross-sectional study.
Child Perceptions Questionnaires
Osteogenesis imperfecta
adolescent
brittle bone disease
child
malocclusion
oral health–related quality of life
Journal
Journal of the American Dental Association (1939)
ISSN: 1943-4723
Titre abrégé: J Am Dent Assoc
Pays: England
ID NLM: 7503060
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
17
12
2019
revised:
19
03
2020
accepted:
26
03
2020
entrez:
29
6
2020
pubmed:
1
7
2020
medline:
18
7
2020
Statut:
ppublish
Résumé
The incidence of malocclusion is higher among people with osteogenesis imperfecta (OI) than the general population, and treatment options are limited due to the weak structure of bones and teeth. Focusing on those malocclusion traits that might have a high impact on a patient's oral health-related quality of life (OHRQoL) is warranted. A total of 138 children and adolescents with OI were examined for malocclusion traits. OHRQoL was measured using age-specific versions (8 through 10 years and 11 through 14 years) of the Child Perceptions Questionnaire (CPQ), considering the following domains: oral symptoms, functional limitation, emotional well-being, and social well-being. Higher scores implied worse OHRQoL. Multivariable ordinal logistic regression was used to estimate the association between malocclusion traits and OHRQoL. Among children aged 8 through 10 years (n = 56), the CPQ and its constituent domain scores were relatively similar between those with malocclusion (higher scores) and those without. In the adolescent (n = 82) group aged 11 through 14 years; however, those with posterior crossbite (odds ratio, 5.01; 95% confidence interval, 1.40 to 12.41) or open bite (odds ratio, 3.21; 95% confidence interval, 1.21 to 10.23) experienced statistically significantly higher degrees of functional limitations (a higher functional limitation score) than those without. Adolescents with OI and posterior open bites or crossbites have substantial self-reported functional limitations and worse oral symptoms, which warrants additional investigation and therapeutic trials in an attempt to improve the malocclusion. In addition, the authors found that the CPQ can be a useful tool in a clinical trial of orthodontic interventions in OI.
Sections du résumé
BACKGROUND
BACKGROUND
The incidence of malocclusion is higher among people with osteogenesis imperfecta (OI) than the general population, and treatment options are limited due to the weak structure of bones and teeth. Focusing on those malocclusion traits that might have a high impact on a patient's oral health-related quality of life (OHRQoL) is warranted.
METHODS
METHODS
A total of 138 children and adolescents with OI were examined for malocclusion traits. OHRQoL was measured using age-specific versions (8 through 10 years and 11 through 14 years) of the Child Perceptions Questionnaire (CPQ), considering the following domains: oral symptoms, functional limitation, emotional well-being, and social well-being. Higher scores implied worse OHRQoL. Multivariable ordinal logistic regression was used to estimate the association between malocclusion traits and OHRQoL.
RESULTS
RESULTS
Among children aged 8 through 10 years (n = 56), the CPQ and its constituent domain scores were relatively similar between those with malocclusion (higher scores) and those without. In the adolescent (n = 82) group aged 11 through 14 years; however, those with posterior crossbite (odds ratio, 5.01; 95% confidence interval, 1.40 to 12.41) or open bite (odds ratio, 3.21; 95% confidence interval, 1.21 to 10.23) experienced statistically significantly higher degrees of functional limitations (a higher functional limitation score) than those without.
CONCLUSIONS
CONCLUSIONS
Adolescents with OI and posterior open bites or crossbites have substantial self-reported functional limitations and worse oral symptoms, which warrants additional investigation and therapeutic trials in an attempt to improve the malocclusion. In addition, the authors found that the CPQ can be a useful tool in a clinical trial of orthodontic interventions in OI.
Identifiants
pubmed: 32593350
pii: S0002-8177(20)30257-9
doi: 10.1016/j.adaj.2020.03.040
pmc: PMC7360479
mid: NIHMS1582684
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
480-490.e2Subventions
Organisme : NIAMS NIH HHS
ID : U54 AR068069
Pays : United States
Investigateurs
Brendan Lee
(B)
V Reid Sutton
(VR)
Sandesh C S Nagamani
(SCS)
Frank Rauch
(F)
Francis Glorieux
(F)
Jean-Marc Retrouvey
(JM)
Paul Esposito
(P)
Maegen Wallace
(M)
Michael B Bober
(MB)
David Eyre
(D)
Danielle Gomez
(D)
Gerald Harris
(G)
Tracy Hart
(T)
Mahim Jain
(M)
Deborah Krakow
(D)
Jeffrey Krischer
(J)
Eric Orwoll
(E)
Lindsey Nicol
(L)
Cathleen Raggio
(C)
Peter Smith
(P)
Laura Tosi
(L)
Informations de copyright
Copyright © 2020 American Dental Association. Published by Elsevier Inc. All rights reserved.
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