The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger.
Journal
The Journal of pediatrics
ISSN: 1097-6833
Titre abrégé: J Pediatr
Pays: United States
ID NLM: 0375410
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
21
01
2020
revised:
28
02
2020
accepted:
03
04
2020
pubmed:
1
7
2020
medline:
29
12
2020
entrez:
29
6
2020
Statut:
ppublish
Résumé
Current screening guidelines in North America for celiac disease recommend additional IgG based testing for younger children. Our multicenter retrospective study showed that the anti-tissue transglutaminase IgA antibody test should be the recommended initial test in all children, including those ≤24 months of age.
Identifiants
pubmed: 32593411
pii: S0022-3476(20)30453-4
doi: 10.1016/j.jpeds.2020.04.009
pmc: PMC7819766
mid: NIHMS1660249
pii:
doi:
Substances chimiques
Biomarkers
0
Immunoglobulin A
0
Protein Glutamine gamma Glutamyltransferase 2
EC 2.3.2.13
Transglutaminases
EC 2.3.2.13
GTP-Binding Proteins
EC 3.6.1.-
Types de publication
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
158-161.e2Subventions
Organisme : NIDDK NIH HHS
ID : K23 DK119584
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK007760
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.