Predictors of residual low back pain after acute osteoporotic compression fracture.

Female Fractures, Compression / complications Humans Low Back Pain / diagnostic imaging Osteoporotic Fractures / complications Prospective Studies Spinal Fractures / complications Treatment Outcome

Journal

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
ISSN: 1436-2023
Titre abrégé: J Orthop Sci
Pays: Japan
ID NLM: 9604934

Informations de publication

Date de publication:
May 2021
Historique:
received: 19 03 2020
revised: 13 04 2020
accepted: 15 04 2020
pubmed: 1 7 2020
medline: 30 9 2021
entrez: 29 6 2020
Statut: ppublish

Résumé

Studies on the clinical and radiographic risk factors for the residual low back pain beyond 6 months after osteoporotic vertebral fractures (OVFs) are lacking. Hence, this study aimed to characterize a patient population with residual low back pain 48 weeks after acute OVFs and to identify the risk factors associated with residual low back pain. This prospective multicenter study included 166 female patients aged 65-85 years with acute one-level OVFs. We defined the residual low back pain as visual analog scale (VAS) for low back pain ≥3.5 at 48 weeks in this study, as VAS score ≥3.5 is used to describe moderate or severe pain. Thus, outcome and risk factor analyses were performed by comparing patients with VAS scores <3.5 and ≥ 3.5. In the radiographic analysis, the anterior vertebral body compression percentage was measured at 0, 12, and 48 weeks. Magnetic resonance imaging (MRI) was performed at enrollment and 48 weeks. Of the 166 patients analyzed, 58 complained of residual low back pain at 48 weeks after OVFs. At 0 weeks, the VAS score was significantly higher, and the JOABPEQ mental health score and anterior vertebral body compression percentage were significantly lower in patients with persistent pain 48 weeks after OVFs. The independent risk factors in the acute phase for persistent pain 48 weeks after OVFs were a high VAS score, MRI T2 fluid-intensity image pattern, and a lower anterior vertebral body compression percentage. Severe low back pain, MRI T2 fluid-intensity image pattern, and severe vertebral body collapse in the acute phase were significant risk factors for residual low back pain 48 weeks after OVFs. Patients with acute OVFs who have these risk factors should be carefully monitored for the possible development of residual chronic low back pain.

Sections du résumé

BACKGROUND BACKGROUND
Studies on the clinical and radiographic risk factors for the residual low back pain beyond 6 months after osteoporotic vertebral fractures (OVFs) are lacking. Hence, this study aimed to characterize a patient population with residual low back pain 48 weeks after acute OVFs and to identify the risk factors associated with residual low back pain.
METHODS METHODS
This prospective multicenter study included 166 female patients aged 65-85 years with acute one-level OVFs. We defined the residual low back pain as visual analog scale (VAS) for low back pain ≥3.5 at 48 weeks in this study, as VAS score ≥3.5 is used to describe moderate or severe pain. Thus, outcome and risk factor analyses were performed by comparing patients with VAS scores <3.5 and ≥ 3.5. In the radiographic analysis, the anterior vertebral body compression percentage was measured at 0, 12, and 48 weeks. Magnetic resonance imaging (MRI) was performed at enrollment and 48 weeks.
RESULTS RESULTS
Of the 166 patients analyzed, 58 complained of residual low back pain at 48 weeks after OVFs. At 0 weeks, the VAS score was significantly higher, and the JOABPEQ mental health score and anterior vertebral body compression percentage were significantly lower in patients with persistent pain 48 weeks after OVFs. The independent risk factors in the acute phase for persistent pain 48 weeks after OVFs were a high VAS score, MRI T2 fluid-intensity image pattern, and a lower anterior vertebral body compression percentage.
CONCLUSIONS CONCLUSIONS
Severe low back pain, MRI T2 fluid-intensity image pattern, and severe vertebral body collapse in the acute phase were significant risk factors for residual low back pain 48 weeks after OVFs. Patients with acute OVFs who have these risk factors should be carefully monitored for the possible development of residual chronic low back pain.

Identifiants

DOI: 10.1016/j.jos.2020.04.015 PMID: 32593545
pubmed: 32593545
pii: S0949-2658(20)30135-4
doi: 10.1016/j.jos.2020.04.015
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

453-458

Informations de copyright

Copyright © 2020 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest Hiroaki Nakamura is an associate editor of Journal of Orthopaedic Science. There are no other conflicts of interest.

Auteurs

Hiroyuki Inose (H)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. Electronic address: inose.orth@tmd.ac.jp.

Tsuyoshi Kato (T)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan; Department of Orthopaedics, Ome Municipal General Hospital, Tokyo, 198-0042, Japan. Electronic address: kato.orth@tmd.ac.jp.

Shoichi Ichimura (S)

Department of Orthopaedics, Kyorin University, Tokyo, 181-8611, Japan. Electronic address: ichimura@ks.kyorin-u.ac.jp.

Hiroaki Nakamura (H)

Department of Orthopedic Surgery, Graduate School of Medicine, Osaka City University, Osaka, 545-8585, Japan. Electronic address: hnakamura@med.osaka-cu.ac.jp.

Masatoshi Hoshino (M)

Department of Orthopedic Surgery, Graduate School of Medicine, Osaka City University, Osaka, 545-8585, Japan. Electronic address: hoshino717@gmail.com.

Daisuke Togawa (D)

Department of Orthopaedic Surgery, Hamamatsu University of Medicine, Shizuoka, 431-3192, Japan. Electronic address: daisuketogawa@wish.ocn.ne.jp.

Toru Hirano (T)

Department of Orthopedic Surgery, Niigata University Medical and Dental Hospital, Niigata, 951-8520, Japan. Electronic address: thirano@med.niigata-u.ac.jp.

Yasuaki Tokuhashi (Y)

Department of Orthopaedic Surgery, Nihon University, Tokyo, 173-8610, Japan. Electronic address: maruto10@gmail.com.

Tetsuro Ohba (T)

Department of Orthopaedic Surgery, University of Yamanashi, Yamanashi, 409-3898, Japan. Electronic address: tooba@yamanashi.ac.jp.

Hirotaka Haro (H)

Department of Orthopaedic Surgery, University of Yamanashi, Yamanashi, 409-3898, Japan. Electronic address: haro@yamanashi.ac.jp.

Takashi Tsuji (T)

Department of Orthopaedic Surgery, Kitasato University Kitasato Institute Hospital, Tokyo, 108-8642, Japan. Electronic address: tsuji9@gmail.com.

Kimiaki Sato (K)

Department of Orthopaedic Surgery, Kurume University School of Medicine, Kurume University, Fukuoka, 830-0011, Japan. Electronic address: kimiaki@med.kurume-u.ac.jp.

Yutaka Sasao (Y)

Department of Orthopaedic Surgery, International University of Health and Welfare Mita Hospital, Tokyo, 108-8329, Japan; Department of Orthopaedic Surgery, Graduate School, School of Medicine, St. Marianna University, Kanagawa, 216-8511, Japan. Electronic address: sasaospine@marianna-u.ac.jp.

Masahiko Takahata (M)

Department of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Hokkaido, 060-8638, Japan. Electronic address: takahatamasahiko@hotmail.co.jp.

Koji Otani (K)

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan. Electronic address: kotani@fmu.ac.jp.

Suketaka Momoshima (S)

Department of Diagnostic Radiology, Center for Preventive Medicine, Keio University School of Medicine, Tokyo, 160-8582, Japan. Electronic address: momo@rad.med.keio.ac.jp.

Masato Yuasa (M)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. Electronic address: yuasa.orth@tmd.ac.jp.

Takashi Hirai (T)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. Electronic address: hirai.orth@tmd.ac.jp.

Toshitaka Yoshii (T)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. Electronic address: yoshii.orth@tmd.ac.jp.

Atsushi Okawa (A)

Department of Orthopaedics, Graduate School, Tokyo Medical and Dental University, Tokyo, 108-0075, Japan. Electronic address: okawa.orth@tmd.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Fractures par compression › Predictors of residual low back pain after...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Predictors of residual low back pain after...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Dorsalgie › Lombalgie › Predictors of residual low back pain after...
questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Fractures ostéoporotiques › Predictors of residual low back pain after...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Predictors of residual low back pain after...
questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Fractures du rachis › Predictors of residual low back pain after...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Predictors of residual low back pain after...