Synthesis and Evaluation of Antimycobacterial and Antiplasmodial Activities of Hirsutellide A and Its Analogues.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
23 Jun 2020
Historique:
received: 09 03 2020
accepted: 08 05 2020
entrez: 30 6 2020
pubmed: 1 7 2020
medline: 1 7 2020
Statut: epublish

Résumé

Hirsutellide A is nature-derived cyclic hexadepsipeptide with reported antimycobacterial and antiplasmodial activities. To verify its structure, hirsutellide A was synthesized following a solution-phase peptide synthesis approach. A detailed analysis of the

Identifiants

pubmed: 32596583
doi: 10.1021/acsomega.0c01065
pmc: PMC7315603
doi:

Types de publication

Journal Article

Langues

eng

Pagination

14451-14460

Informations de copyright

Copyright © 2020 American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Henok Asfaw Sahile (HA)

Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, Germany.
Division of Infectious Diseases, Departments of Medicine, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia, V6T 1Z3 Canada.

Maria Santos Martínez-Martínez (MS)

Diseases of the Developing World, Medicines Development Campus, GlaxoSmithKline, Calle de Severo Ochoa, 2, 28760 Tres Cantos, Madrid, Spain.

Melissa Dillenberger (M)

Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.

Katja Becker (K)

Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.

Peter Imming (P)

Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, 06120 Halle, Germany.

Classifications MeSH