Predictors and Outcomes of Cardiac Events following Thoracic Endovascular Aortic Repair in Descending Thoracic Aortic Aneurysm and Dissection.


Journal

Aorta (Stamford, Conn.)
ISSN: 2325-4637
Titre abrégé: Aorta (Stamford)
Pays: Germany
ID NLM: 101655549

Informations de publication

Date de publication:
Feb 2020
Historique:
entrez: 30 6 2020
pubmed: 1 7 2020
medline: 1 7 2020
Statut: ppublish

Résumé

 Cardiac events following thoracic endovascular aortic repair (TEVAR) have been associated with significant morbidity and mortality. However, predictors of post-TEVAR cardiac events in descending thoracic aortic aneurysm or dissection are poorly understood.  A retrospective analysis of completed TEVAR procedures performed from 2010 to 2016 was conducted using the ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Program) participant user file database. Adult patients (≥18 years) who underwent TEVAR for descending thoracic aortic aneurysm or dissection were identified and 30-day outcomes were examined. An initial univariate analysis was performed to determine associations between all patient variables and cardiac events, defined as myocardial infarction or cardiac arrest that occurred ≤30 days of surgery. Multivariate logistic regression was subsequently performed to identify independent risk factors for cardiac events following TEVAR.  The study identified 150 out of 2,905 (5.2%) patients who underwent TEVAR for descending thoracic aortic aneurysm or dissection who developed cardiac events. No significant difference in incidence of cardiac events was noted among patients presenting with aortic aneurysm or dissection (  Cardiac events following TEVAR are associated with significant mortality. Patients with these risk factors should be appropriately monitored to improve outcomes.

Sections du résumé

BACKGROUND BACKGROUND
 Cardiac events following thoracic endovascular aortic repair (TEVAR) have been associated with significant morbidity and mortality. However, predictors of post-TEVAR cardiac events in descending thoracic aortic aneurysm or dissection are poorly understood.
METHODS METHODS
 A retrospective analysis of completed TEVAR procedures performed from 2010 to 2016 was conducted using the ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Program) participant user file database. Adult patients (≥18 years) who underwent TEVAR for descending thoracic aortic aneurysm or dissection were identified and 30-day outcomes were examined. An initial univariate analysis was performed to determine associations between all patient variables and cardiac events, defined as myocardial infarction or cardiac arrest that occurred ≤30 days of surgery. Multivariate logistic regression was subsequently performed to identify independent risk factors for cardiac events following TEVAR.
RESULTS RESULTS
 The study identified 150 out of 2,905 (5.2%) patients who underwent TEVAR for descending thoracic aortic aneurysm or dissection who developed cardiac events. No significant difference in incidence of cardiac events was noted among patients presenting with aortic aneurysm or dissection (
CONCLUSIONS CONCLUSIONS
 Cardiac events following TEVAR are associated with significant mortality. Patients with these risk factors should be appropriately monitored to improve outcomes.

Identifiants

pubmed: 32599627
doi: 10.1055/s-0040-1701606
pmc: PMC7324254
doi:

Types de publication

Journal Article

Langues

eng

Pagination

6-13

Informations de copyright

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest related to this article.

Références

Ann Thorac Surg. 2008 Nov;86(5):1707-12
pubmed: 19049790
Semin Thorac Cardiovasc Surg. 2009 Winter;21(4):341-6
pubmed: 20226348
J Vasc Surg. 2010 Feb;51(2):351-8; discussion 358-9
pubmed: 20141958
J Vasc Surg. 2014 Nov;60(5):1196-1203
pubmed: 24973286
Circulation. 2013 Jan 1;127(1):24-32
pubmed: 23283856
Blood Transfus. 2009 Jan;7(1):49-64
pubmed: 19290081
Eur J Vasc Endovasc Surg. 2014 Jul;48(1):13-22
pubmed: 24785650
Arch Dis Child. 1999 May;80(5):475-80
pubmed: 10208959
Ann Thorac Surg. 2013 May;95(5):1577-83
pubmed: 23566647
Clin J Am Soc Nephrol. 2007 May;2(3):410-2
pubmed: 17699443
Crit Care Med. 2016 Dec;44(12):2199-2207
pubmed: 27441906
J Vasc Surg. 1986 Feb;3(2):338-42
pubmed: 3944935
Crit Care Resusc. 1999 Dec;1(4):388-99
pubmed: 16599883
Circulation. 2011 Dec 13;124(24):2661-9
pubmed: 22104552
Anesthesiology. 2011 Jul;115(1):44-53
pubmed: 21552116
Ann Surg. 2013 Dec;258(6):1096-102
pubmed: 23511839
Indian J Anaesth. 2014 Sep;58(5):643-6
pubmed: 25535429
Ann Transl Med. 2016 Oct;4(20):393
pubmed: 27867945
Vasc Endovascular Surg. 2017 Apr;51(3):131-138
pubmed: 28330439
Circulation. 2003 Sep 9;108 Suppl 1:II312-7
pubmed: 12970252
Am J Kidney Dis. 2017 Jul;70(1):84-92
pubmed: 28196648
Ann Surg. 2015 Mar;261(3):432-7
pubmed: 24887971
JAMA. 2002 Sep 25;288(12):1499-507
pubmed: 12243637
Circulation. 2007 Nov 27;116(22):2544-52
pubmed: 17998460
J Vasc Surg. 1993 Feb;17(2):357-68; discussion 368-70
pubmed: 8433431
Eur J Cardiothorac Surg. 2012 Jul;42(1):17-24
pubmed: 22561652
J Vasc Surg. 2010 Sep;52(3):674-83, 683.e1-683.e3
pubmed: 20570467
J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1523-1529
pubmed: 27595531
Ann Vasc Dis. 2017 Jun 25;10(2):79-87
pubmed: 29034031
Vasc Endovascular Surg. 2010 Jan;44(1):14-9
pubmed: 19828579
J Vasc Surg. 2012 Nov;56(5):1266-72; discussion 1272-3
pubmed: 22840739
PLoS One. 2017 Sep 5;12(9):e0182118
pubmed: 28873411
Ann Surg. 2007 May;245(5):672-3
pubmed: 17457157
Surg Clin North Am. 2005 Dec;85(6):1215-27, x
pubmed: 16326203
J Vasc Surg. 2011 Jan;53(1):21-27.e1-2
pubmed: 21184931
Eur J Anaesthesiol. 2011 Mar;28(3):220-4
pubmed: 21191304
Ann Surg. 2002 Sep;236(3):344-53; discussion 353-4
pubmed: 12192321
J Vasc Surg. 2010 Mar;51(3):616-21, 621.e1-3
pubmed: 20110154
Eur J Vasc Endovasc Surg. 2009 Mar;37(3):311-8
pubmed: 19111480
J Vasc Surg. 2010 Dec;52(6):1464-70
pubmed: 20855177
Semin Vasc Surg. 2014 Dec;27(3-4):162-9
pubmed: 26073826

Auteurs

Derrick O Acheampong (DO)

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Philip Paul (P)

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Percy Boateng (P)

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

I Michael Leitman (IM)

Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Classifications MeSH