Occipital intracerebral hemorrhage-clinical characteristics, outcome, and post-ICH epilepsy.
cerebral hemorrhage
epilepsy
occipital lobe
outcome
visual fields
Journal
Acta neurologica Scandinavica
ISSN: 1600-0404
Titre abrégé: Acta Neurol Scand
Pays: Denmark
ID NLM: 0370336
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
08
04
2020
revised:
09
06
2020
accepted:
21
06
2020
pubmed:
1
7
2020
medline:
20
4
2021
entrez:
1
7
2020
Statut:
ppublish
Résumé
Posterior location affects the clinical presentation and outcome of ischemic stroke, but little is known about occipital intracerebral hemorrhage (ICH). We studied non-traumatic occipital ICH phenotype, outcome, and post-ICH epilepsy. Occipital ICH patients were retrospectively identified from the Helsinki ICH Study registry of 1013 consecutive ICH patients treated in our tertiary center in 2005-2010. They were compared to non-occipital ICH patients to evaluate the effect of location on functional outcome at discharge (dichotomized modified Rankin Scale, mRS), 3- and 12-month mortality, and incidence of epilepsy. We found 19 occipital ICH patients (5.3% of lobar and 1.9% of all ICH). Compared to non-occipital lobar ICHs, they were younger (median age 63 vs 71 years, P = .007) and had lower National Institutes of Health Stroke Scale on admission (1 vs 8, P < .001), smaller hematoma volume (6.3 vs 17.7 ML, P = .008), and more frequently structural etiology underlying the ICH (26% vs 7%, P = .01). Mortality at both 3 and 12 months was 6%, whereas 84% reached favorable outcome (mRS 0-2) at discharge. Occipital location was associated with favorable outcome at discharge in lobar ICH (OR 11.02, 95% CI 1.55-78.20). Incidence of post-ICH epilepsy (median follow-up 2.7 years) was 18%, equaling to that of non-occipital lobar ICH. Occipital ICH patients are younger, have less severe clinical presentation, smaller hematoma volume, more often structural etiology, and better outcome than other ICH patients. They exhibit a similar risk of epilepsy as non-occipital ICHs.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
71-77Subventions
Organisme : Finnish Government
Organisme : Maire Taponen Foundation
Organisme : Finnish Medical Foundation
Organisme : Biomedicum Helsinki Foundation
Informations de copyright
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Références
van Asch CJ, Luitse MJ, Rinkel GJ, vander Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol. 2010;9(2):167-176.
Feigin VL, Nguyen G, Cercy K, et al. Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J Med. 2018;379(25):2429-2437.
Poon MTC, Fonville AF, Al-Shahi SR. Long-term prognosis after intracerebral haemorrhage: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2014;85(6):660-667.
Sreekrishnan A, Dearborn JL, Greer DM, et al. Intracerebral hemorrhage location and functional outcomes of patients: a systematic literature review and meta-analysis. Neurocrit Care. 2016;25(3):384-391.
Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001;32(4):891-897.
Sembill JA, Gerner ST, Volbers B, et al. Severity assessment in maximally treated ICH patients: the max-ICH score. Neurology. 2017;89(5):423-431.
Meretoja A, Strbian D, Putaala J, et al. SMASH-U: a proposal for etiologic classification of intracerebral hemorrhage. Stroke. 2012;43(10):2592-2597.
Rost NS, Smith EE, Chang Y, et al. Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score. Stroke. 2008;39(8):2304-2309.
Wu O, Cloonan L, Mocking SJT, et al. Role of acute lesion topography in initial ischemic stroke severity and long-term functional outcomes. Stroke. 2015;46(9):2438-2444.
Heuts-van Raak L, Lodder J, Kessels F. Late seizures following a first symptomatic brain infarct are related to large infarcts involving the posterior area around the lateral sulcus. Seizure. 1996;5(3):185-194.
Gerner ST, Kuramatsu JB, Moeller S, et al. Specific lobar affection reveals a rostrocaudal gradient in functional outcome in spontaneous intracerebral hemorrhage. Stroke. 2017;48(3):587-595.
Lee J-Y, King C, Stradling D, et al. Influence of hematoma location on acute mortality after intracerebral hemorrhage. J Neuroimaging. 2014;24(2):131-136.
Haapaniemi E, Strbian D, Rossi C, et al. The CAVE score for predicting late seizures after intracerebral hemorrhage. Stroke. 2014;45(7):1971-1976.
Wu TY, Sobowale O, Hurford R, et al. Software output from semi-automated planimetry can underestimate intracerebral haemorrhage and peri-haematomal oedema volumes by up to 41. Neuroradiology. 2016;58(9):867-876.
Wu TY, Yassi N, Shah DG, et al. Simultaneous multiple intracerebral hemorrhages (SMICH). Stroke. 2017;48(3):581-586.
Vinters HV, Gilbert JJ. Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. Stroke. 1983;14(6):924-928.
Allen JS, Damasio H, Grabowski TJ, Bruss J, Zhang W. Sexual dimorphism and asymmetries in the gray-white composition of the human cerebrum. NeuroImage. 2003;18(4):880-894.
Martin PJ, Evans DH, Naylor AR. Transcranial color-coded sonography of the basal cerebral circulation. Reference data from 115 volunteers. Stroke. 1994;25(2):390-396.
Broderick JP, Diringer MN, Hill MD, et al. Determinants of intracerebral hemorrhage growth: an exploratory analysis. Stroke. 2007;38(3):1072-1075.
Räty S, Silvennoinen K, Tatlisumak T. Prehospital pathways of occipital stroke patients with mainly visual symptoms. Acta Neurol Scand. 2018;137(1):51-58.
Murthy SB, Merkler AE, Omran SS, et al. Outcomes after intracerebral hemorrhage from arteriovenous malformations. Neurology. 2017;88(20):1882-1888.
Crawford PM, West CR, Chadwick DW, Shaw MD. Arteriovenous malformations of the brain: natural history in unoperated patients. J Neurol Neurosurg Psychiatry. 1986;49(1):1-10.
Gray CS, French JM, Bates D, Cartlidge NE, Venables GS, James OF. Recovery of visual fields in acute stroke: homonymous hemianopia associated with adverse prognosis. Age Ageing. 1989;18(6):419-421.
Tiel K, Kolmel HW. Patterns of recovery from homonymous hemianopia subsequent to infarction in the distribution of the posterior cerebral artery. Neuro-Ophthalmol. 1991;11(1):33-39.
Zhang X, Kedar S, Lynn MJ, Newman NJ, Biousse V. Natural history of homonymous hemianopia. Neurology. 2006;66(6):901-905.
Pandit RJ, Gales K, Griffiths PG. Effectiveness of testing visual fields by confrontation. Lancet. 2001;358(9290):1339-1340.
Ntaios G, Spengos K, Vemmou AM, et al. Long-term outcome in posterior cerebral artery stroke. Eur J Neurol. 2011;18(8):1074-1080.
Cals N, Devuyst G, Afsar N, Karapanayiotides T, Bogousslavsky J. Pure superficial posterior cerebral artery territory infarction in The Lausanne Stroke Registry. J Neurol. 2002;249(7):855-861.
Kumral E, Bayulkem G, Ataç C, Alper Y. Spectrum of superficial posterior cerebral artery territory infarcts. Eur J Neurol. 2004;11(4):237-246.
de Haan R, Limburg M, Bossuyt P, vander Meulen J, Aaronson N. The clinical meaning of Rankin 'handicap' grades after stroke. Stroke. 1995;26(11):2027-2030.
De Reuck J, Hemelsoet D, Van Maele G. Seizures and epilepsy in patients with a spontaneous intracerebral haematoma. Clin Neurol Neurosurg. 2007;109(6):501-504.
Merkler AE, Gialdini G, Lerario MP, et al. Population-based assessment of the long-term risk of seizures in survivors of stroke. Stroke. 2018;49(6):1319-1324.
Yang T-M, Lin W-C, Chang W-N, et al. Predictors and outcome of seizures after spontaneous intracerebral hemorrhage. Clinical article. J Neurosurg. 2009;111(1):87-93.