Sound and Vibration as Research Variables in Terrestrial Vertebrate Models.

laboratory animal noise research variable sound vibration

Journal

ILAR journal
ISSN: 1930-6180
Titre abrégé: ILAR J
Pays: England
ID NLM: 9516416

Informations de publication

Date de publication:
19 10 2020
Historique:
received: 28 02 2019
revised: 07 02 2020
accepted: 11 02 2020
pubmed: 1 7 2020
medline: 3 11 2021
entrez: 1 7 2020
Statut: ppublish

Résumé

Sound and vibration have been shown to alter animal behavior and induce physiological changes as well as to cause effects at the cellular and molecular level. For these reasons, both environmental factors have a considerable potential to alter research outcomes when the outcome of the study is dependent on the animal existing in a normal or predictable biological state. Determining the specific levels of sound or vibration that will alter research is complex, as species will respond to different frequencies and have varying frequencies where they are most sensitive. In consideration of the potential of these factors to alter research, a thorough review of the literature and the conditions that likely exist in the research facility should occur specific to each research study. This review will summarize the fundamental physical properties of sound and vibration in relation to deriving maximal level standards, consider the sources of exposure, review the effects on animals, and discuss means by which the adverse effects of these factors can be mitigated.

Identifiants

pubmed: 32602530
pii: 5864984
doi: 10.1093/ilar/ilaa004
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

159-174

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press on behalf of the National Academies of Sciences, Engineering, and Medicine. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Auteurs

Randall Reynolds (R)

Duke University School of Medicine, Department of Pathology and Division of Laboratory Animal Resources, Durham, NC.

Angela Garner (A)

Duke University School of Medicine, Division of Laboratory Animal Resources, Durham, NC.

John Norton (J)

Duke University School of Medicine, Pathology and Division of Laboratory Animal Resources.

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Classifications MeSH