Degradation of
Apoptosis
/ drug effects
Ascorbic Acid
/ pharmacology
Caspases
/ metabolism
Cell Line, Tumor
Cell Survival
/ drug effects
Cytochromes c
/ metabolism
Humans
Hydrogen Peroxide
/ pharmacology
Lung Neoplasms
Membrane Potential, Mitochondrial
/ drug effects
Polysaccharides
/ chemistry
Proto-Oncogene Proteins c-akt
/ metabolism
Proto-Oncogene Proteins c-bcl-2
/ metabolism
Sargassum
/ chemistry
Signal Transduction
TOR Serine-Threonine Kinases
/ metabolism
Sargassum crassifolium
anti-lung cancer
apoptosis
ascorbic acid
brown algae
fucoidan
human lung carcinoma A-549 cells
hydrogen peroxide
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
26 Jun 2020
26 Jun 2020
Historique:
received:
09
05
2020
revised:
20
06
2020
accepted:
24
06
2020
entrez:
2
7
2020
pubmed:
2
7
2020
medline:
28
4
2021
Statut:
epublish
Résumé
Fucoidans possess multiple biological functions including anti-cancer activity. Moreover, low-molecular-weight fucoidans are reported to possess more bioactivities than native fucoidans. In the present study, a native fucoidan (SC) was extracted from
Identifiants
pubmed: 32604764
pii: md18060334
doi: 10.3390/md18060334
pmc: PMC7345171
pii:
doi:
Substances chimiques
BCL2 protein, human
0
Polysaccharides
0
Proto-Oncogene Proteins c-bcl-2
0
Cytochromes c
9007-43-6
fucoidan
9072-19-9
Hydrogen Peroxide
BBX060AN9V
MTOR protein, human
EC 2.7.1.1
AKT1 protein, human
EC 2.7.11.1
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
TOR Serine-Threonine Kinases
EC 2.7.11.1
Caspases
EC 3.4.22.-
Ascorbic Acid
PQ6CK8PD0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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