Newly Identified Regulators of Ovarian Folliculogenesis and Ovulation.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 Jun 2020
Historique:
received: 07 05 2020
revised: 19 06 2020
accepted: 23 06 2020
entrez: 2 7 2020
pubmed: 2 7 2020
medline: 23 3 2021
Statut: epublish

Résumé

Each follicle represents the basic functional unit of the ovary. From its very initial stage of development, the follicle consists of an oocyte surrounded by somatic cells. The oocyte grows and matures to become fertilizable and the somatic cells proliferate and differentiate into the major suppliers of steroid sex hormones as well as generators of other local regulators. The process by which a follicle forms, proceeds through several growing stages, develops to eventually release the mature oocyte, and turns into a corpus luteum (CL) is known as "folliculogenesis". The task of this review is to define the different stages of folliculogenesis culminating at ovulation and CL formation, and to summarize the most recent information regarding the newly identified factors that regulate the specific stages of this highly intricated process. This information comprises of either novel regulators involved in ovarian biology, such as

Identifiants

pubmed: 32604954
pii: ijms21124565
doi: 10.3390/ijms21124565
pmc: PMC7349727
pii:
doi:

Substances chimiques

Gonadal Steroid Hormones 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Eran Gershon (E)

Department of Ruminant Science, Agricultural Research Organization, PO Box 6, Rishon LeZion 50250, Israel.

Nava Dekel (N)

Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.

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