Hepatic Xanthogranuloma that Originated from a Liver Cyst and Mimicked a Malignant Tumor.


Journal

In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809

Informations de publication

Date de publication:
Historique:
received: 01 04 2020
revised: 17 04 2020
accepted: 24 04 2020
entrez: 2 7 2020
pubmed: 2 7 2020
medline: 22 6 2021
Statut: ppublish

Résumé

Hepatic xanthogranuloma is a very rale disease and formation process is unknown. A 69-year-old woman previously diagnosed as simple liver cyst. Two years before, a 36-mm liver cyst was found in segment 5, while one year later, the hemorrhagic cyst was 40 mm in diameter and a thin septum had formed. The most recent T1-weighted magnetic resonance imaging (MRI) showed a regular 21-mm hepatic mass with a hyperintense 11-mm center and a hypointense periphery. Peripheral enhancement was seen on gadolinium enhanced MRI. Hepatobiliary cystadenoma or cystadenocarcinoma was suspected because of wall thickness and slight enhancement. Microscopic examination following laparoscopic partial liver resection revealed fibroblasts, dense collagen fibers, and a double layer of hemosiderin-laden as well as foamy macrophages attached to the fibrous capsule. The patient was diagnosed with a hepatic xanthogranuloma that originated from a hemorrhagic liver cyst. Intracystic hemorrhage may be one of the reasons for hepatic xanthogranuloma formation.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
Hepatic xanthogranuloma is a very rale disease and formation process is unknown.
CASE REPORT METHODS
A 69-year-old woman previously diagnosed as simple liver cyst. Two years before, a 36-mm liver cyst was found in segment 5, while one year later, the hemorrhagic cyst was 40 mm in diameter and a thin septum had formed. The most recent T1-weighted magnetic resonance imaging (MRI) showed a regular 21-mm hepatic mass with a hyperintense 11-mm center and a hypointense periphery. Peripheral enhancement was seen on gadolinium enhanced MRI. Hepatobiliary cystadenoma or cystadenocarcinoma was suspected because of wall thickness and slight enhancement. Microscopic examination following laparoscopic partial liver resection revealed fibroblasts, dense collagen fibers, and a double layer of hemosiderin-laden as well as foamy macrophages attached to the fibrous capsule.
CONCLUSION CONCLUSIONS
The patient was diagnosed with a hepatic xanthogranuloma that originated from a hemorrhagic liver cyst. Intracystic hemorrhage may be one of the reasons for hepatic xanthogranuloma formation.

Identifiants

pubmed: 32606184
pii: 34/4/2067
doi: 10.21873/invivo.12009
pmc: PMC7439875
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2067-2071

Informations de copyright

Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Références

Arch Pathol Lab Med. 1993 Feb;117(2):157-9
pubmed: 8427563
J Med Case Rep. 2014 Oct 21;8:349
pubmed: 25335527
World J Gastroenterol. 2006 Mar 21;12(11):1798-801
pubmed: 16586558
ANZ J Surg. 2012 Sep;82(9):663-5
pubmed: 22943093
Am J Clin Pathol. 1978 Feb;69(2):176-81
pubmed: 629225
J Gastroenterol Hepatol. 2017 Oct;32(10):1667
pubmed: 28948701
J Cutan Pathol. 1995 Aug;22(4):327-35
pubmed: 7499572
Ann Surg. 2018 Feb;267(2):208-209
pubmed: 29064901
Ann Surg. 2005 May;241(5):769-73; discussion 773-5
pubmed: 15849512
J Am Coll Surg. 2005 May;200(5):727-33
pubmed: 15848365
AJR Am J Roentgenol. 2007 Oct;189(4):W202-4
pubmed: 17885031
World J Gastroenterol. 2015 Nov 28;21(44):12653-9
pubmed: 26640342
Am J Surg Pathol. 2003 May;27(5):579-93
pubmed: 12717244
Cancer. 1977 Jan;39(1):322-38
pubmed: 318915
J Hepatobiliary Pancreat Sci. 2015 Oct;22(10):711-20
pubmed: 25902703
HPB (Oxford). 2014 May;16(5):448-58
pubmed: 23991684
World J Surg Oncol. 2008 Dec 11;6:129
pubmed: 19077232
World J Gastroenterol. 2013 Nov 21;19(43):7603-19
pubmed: 24282350

Auteurs

Eri Oda (E)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Toru Beppu (T)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan tbeppu@yamaga-mc.jp.

Koichi Kinoshita (K)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Kensuke Yamamura (K)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Nobutaka Sato (N)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Hideaki Yuki (H)

Department of Radiology, Yamaga City Medical Center, Kumamoto, Japan.

Suguru Chiyonaga (S)

Department of Gastroenterology, Yamaga City Medical Center, Kumamoto, Japan.

Toshihiko Motohara (T)

Department of Gastroenterology, Yamaga City Medical Center, Kumamoto, Japan.

Yoshihiko Komohara (Y)

Department of Cell Pathology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.

Shinichi Akahoshi (S)

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH