Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice.
Journal
Molecular psychiatry
ISSN: 1476-5578
Titre abrégé: Mol Psychiatry
Pays: England
ID NLM: 9607835
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
02
03
2019
accepted:
12
06
2020
revised:
03
06
2020
pubmed:
2
7
2020
medline:
1
2
2022
entrez:
2
7
2020
Statut:
ppublish
Résumé
Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1
Identifiants
pubmed: 32606374
doi: 10.1038/s41380-020-0821-6
pii: 10.1038/s41380-020-0821-6
pmc: PMC8095717
mid: NIHMS1603614
doi:
Substances chimiques
Fmr1 protein, mouse
0
Receptors, N-Methyl-D-Aspartate
0
Fragile X Mental Retardation Protein
139135-51-6
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4652-4669Subventions
Organisme : NEI NIH HHS
ID : R01 EY023037
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH106469
Pays : United States
Informations de copyright
© 2020. The Author(s).
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