Evaluation of Intraocular Pressure After Water Drinking Test in Patients with Unilateral Hemifacial Spasm.

glaucoma hemifacial spasm intraocular pressure water drinking test

Journal

Clinical ophthalmology (Auckland, N.Z.)
ISSN: 1177-5467
Titre abrégé: Clin Ophthalmol
Pays: New Zealand
ID NLM: 101321512

Informations de publication

Date de publication:
2020
Historique:
received: 15 02 2020
accepted: 15 04 2020
entrez: 2 7 2020
pubmed: 2 7 2020
medline: 2 7 2020
Statut: epublish

Résumé

The aim of the study is to examine the baseline intraocular pressure (IOP) and its changes after performing a water drinking test (WDT) in patients with unilateral hemifacial spasm (HFS). In this prospective observational study, patients aged 21 years and above diagnosed with unilateral HFS were recruited from the Singapore National Eye Centre between January 2015 and August 2016. The unaffected eye of each patient served as a matched control. An interviewer-administered standardized questionnaire on HFS symptoms and ophthalmic examination was performed. Automated perimetry, optical coherence tomography (OCT) of the optic nerve head, color disc stereophotography and water drinking test (WDT) were done. The primary outcome measure was the difference in IOP between eyes affected by HFS and fellow eyes at baseline and at 15, 30 and 45 minutes of the WDT. Fifty-four patients with unilateral HFS were included. Mean age was 59.8±9.9 years (range, 37.0-84.0). Of these, 54% were female and 94% were Chinese. Mean baseline IOP was significantly higher in eyes with HFS (13.9±3.1mmHg) compared to fellow eyes (13.3±2.8mmHg) (p=0.008). There was no significant difference in absolute or percentage change in IOP from baseline between the 2 groups at 15, 30 and 45 minutes of the WDT. Mean vertical cup-disc ratio (VCDR) on clinical examination was significantly higher in eyes with HFS (0.5±0.2) compared to fellow eyes (0.4±0.2) (p=0.02). There was no significant difference between the groups for visual field parameters and mean retinal nerve fiber layer thickness on OCT. Hemifacial spasm is associated with a small but significant difference in mean baseline IOP and VCDR between affected and fellow eyes. However, when eyes affected by HFS and fellow eyes were challenged with the WDT, both responded in similar ways.

Identifiants

pubmed: 32606582
doi: 10.2147/OPTH.S249943
pii: 249943
pmc: PMC7308145
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1675-1680

Informations de copyright

© 2020 Low et al.

Déclaration de conflit d'intérêts

Dr Shamira A Perera reports personal fees from Santen, Glaukos, Allergan, Mundipharma, and Alcon Novartis, outside the submitted work. The authors report no other conflicts of interest in this work.

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Auteurs

Jin Rong Low (JR)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Department of Glaucoma, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.

Chee Wai Wong (CW)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Department of Surgical Retina, Singapore National Eye Centre, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
Department of Ophthalmology, National University of Singapore, Singapore.

Jing Liang Loo (JL)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
Department of Ophthalmology, National University of Singapore, Singapore.
Department of Neuro-Ophthalmology, Singapore National Eye Centre, Singapore.
Neuroscience and Behavioral Disorders Program, Duke-NUS Medical School, Singapore.

Dan Milea (D)

Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
Department of Neuro-Ophthalmology, Singapore National Eye Centre, Singapore.
Neuroscience and Behavioral Disorders Program, Duke-NUS Medical School, Singapore.

Shamira A Perera (SA)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Department of Glaucoma, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.

Yi Fang Lee (YF)

Singapore Eye Research Institute, Singapore.
Department of Training and Education, Singapore National Eye Centre, Singapore.

Si Rui Ng (SR)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Department of Glaucoma, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.

Mani Baskaran (M)

Department of Glaucoma, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.

Monisha Esther Nongpiur (ME)

Department of Glaucoma, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.

Sharon Lee Choon Tow (SLC)

Department of Cataract and Comprehensive Ophthalmology, Singapore National Eye Centre, Singapore.
Singapore Eye Research Institute, Singapore.
Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
Department of Ophthalmology, National University of Singapore, Singapore.
Department of Neuro-Ophthalmology, Singapore National Eye Centre, Singapore.
Neuroscience and Behavioral Disorders Program, Duke-NUS Medical School, Singapore.

Classifications MeSH