Coronavirus (COVID-19) Fulminant Myopericarditis and Acute Respiratory Distress Syndrome (ARDS) in a Middle-Aged Male Patient.

ards coronavirus disease (covid-19) diffuse st elevation myocarditis myopericarditis sars-cov-2 (severe acute respiratory syndrome coronavirus -2)

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
24 Jun 2020
Historique:
entrez: 2 7 2020
pubmed: 2 7 2020
medline: 2 7 2020
Statut: epublish

Résumé

Myopericarditis remains a prominent infectious inflammatory disorder throughout a patient's lifetime. Moreover, viral pathogens have been proven to be the leading contributors to myopericarditis in the pediatric and adult populations. Despite the current comprehensive knowledge of myocardial injury in viral and post-viral myopericarditis, the cellular and molecular mechanisms of SARS-CoV-2-induced myopericarditis are poorly understood. This report presents a case of coronavirus (COVID-19) fulminant myopericarditis and acute respiratory distress syndrome (ARDS) in a middle-aged male patient: a 51-year-old man with a history of hypertension who arrived to the emergency department with a dry cough, fatigue, dyspnea, and a fever. A real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay confirmed a diagnosis of COVID-19 infection, resulting in the patient's admission to the airborne isolation unit for clinical observation. When his condition began to deteriorate, the patient was transferred to the cardiac care unit after electrocardiography detected cardiac injury, demonstrating diffuse ST-segment elevation. Laboratory evaluations revealed elevated troponin T and BNP, with an echocardiogram indicating global left ventricular hypokinesia and a reduced ejection fraction. The patient was treated with hydroxychloroquine, azithromycin, dobutamine, remdesivir, and ventilatory support. This specific case highlights the severity and complications that may arise as a direct result of COVID-19 infection.

Identifiants

pubmed: 32607304
doi: 10.7759/cureus.8808
pmc: PMC7320646
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e8808

Informations de copyright

Copyright © 2020, Hussain et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Microbiol Mol Biol Rev. 2005 Dec;69(4):635-64
pubmed: 16339739
Emerg Microbes Infect. 2012 Aug;1(8):e13
pubmed: 26038424

Auteurs

Hussain Hussain (H)

Internal Medicine, Cardiology Clinic, Pasadena, USA.

Aya Fadel (A)

Internal Medicine, Florida International University, Hialeah Hospital, Miami, USA.

Haidar Alwaeli (H)

Medical Education and Simulation, Richmond University Medical Center, New York, USA.

Victor Guardiola (V)

Oncology, Baptist Health South Florida, Miami, USA.

Classifications MeSH