Unsupervised assessment of cognition in the Healthy Brain Project: Implications for web-based registries of individuals at risk for Alzheimer's disease.

Alzheimer's disease acceptability neuropsychological test neuropsychology neuroscience online systems psychological test usability validity

Journal

Alzheimer's & dementia (New York, N. Y.)
ISSN: 2352-8737
Titre abrégé: Alzheimers Dement (N Y)
Pays: United States
ID NLM: 101650118

Informations de publication

Date de publication:
2020
Historique:
received: 20 04 2020
accepted: 26 05 2020
entrez: 2 7 2020
pubmed: 2 7 2020
medline: 2 7 2020
Statut: epublish

Résumé

Web-based platforms are used increasingly to assess cognitive function in unsupervised settings. The utility of cognitive data arising from unsupervised assessments remains unclear. We examined the acceptability, usability, and validity of unsupervised cognitive testing in middle-aged adults enrolled in the Healthy Brain Project. A total of 1594 participants completed unsupervised assessments of the Cogstate Brief Battery. Acceptability was defined by the amount of missing data, and usability by examining error of test performance and the time taken to read task instructions and complete tests (learnability). Overall, we observed high acceptability (98% complete data) and high usability (95% met criteria for low error rates and high learnability). Test validity was confirmed by observation of expected inverse relationships between performance and increasing test difficulty and age. Consideration of test design paired with acceptability and usability criteria can provide valid indices of cognition in the unsupervised settings used to develop registries of individuals at risk for Alzheimer's disease.

Identifiants

pubmed: 32607409
doi: 10.1002/trc2.12043
pii: TRC212043
pmc: PMC7317647
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e12043

Informations de copyright

© 2020 the Alzheimer's Association.

Déclaration de conflit d'intérêts

S Perin, RF Buckley, MP Pase, N Yassi, and YY Lim report no disclosures. A Schembri and P Maruff are full‐time employees of Cogstate Ltd.

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Auteurs

Stephanie Perin (S)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria Australia.
School of Psychology Faculty of Health Sciences Australian Catholic University Melbourne Victoria Australia.

Rachel F Buckley (RF)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
Melbourne School of Psychological Sciences University of Melbourne Parkville Victoria Australia.
Department of Neurology Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA.
Center for Alzheimer Research and Treatment Department of Neurology Brigham and Women's Hospital Boston Massachusetts USA.

Matthew P Pase (MP)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria Australia.
Harvard T.H. Chan School of Public Health Boston Massachusetts USA.

Nawaf Yassi (N)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
Department of Medicine and Neurology Melbourne Brain Centre at The Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.
Population Health and Immunity Division The Walter and Eliza Hall Institute of Medical Research Parkville Victoria Australia.

Alexandra Lavale (A)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria Australia.

Peter H Wilson (PH)

School of Psychology Faculty of Health Sciences Australian Catholic University Melbourne Victoria Australia.

Adrian Schembri (A)

Cogstate Ltd Melbourne Victoria Australia.

Paul Maruff (P)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
Cogstate Ltd Melbourne Victoria Australia.

Yen Ying Lim (YY)

Melbourne Dementia Research Centre Florey Institute of Neuroscience and Mental Health and the University of Melbourne Parkville Victoria Australia.
School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria Australia.

Classifications MeSH