Changes in Abdominal Obesity Affect the Risk of Metachronous Advanced Colorectal Neoplasia Development after Polypectomy.
Adult
Body Mass Index
Colonic Polyps
/ epidemiology
Colonoscopy
/ methods
Colorectal Neoplasms
/ epidemiology
Female
Humans
Male
Middle Aged
Multivariate Analysis
Neoplasms, Second Primary
/ epidemiology
Obesity
/ complications
Obesity, Abdominal
/ complications
Retrospective Studies
Risk Factors
Waist Circumference
/ physiology
Metachronous advanced colorectal neoplasia
obesity
waist circumference
Journal
Yonsei medical journal
ISSN: 1976-2437
Titre abrégé: Yonsei Med J
Pays: Korea (South)
ID NLM: 0414003
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
28
02
2020
revised:
24
05
2020
accepted:
04
06
2020
entrez:
2
7
2020
pubmed:
2
7
2020
medline:
19
8
2020
Statut:
ppublish
Résumé
The impact of changes in body mass index and waist circumference on the development of metachronous colorectal neoplasia (CRN) after polypectomy has rarely been examined. We evaluated the association between changes in overall/abdominal obesity and metachronous CRN risk. We studied patients who underwent ≥1 adenoma removal and surveillance colonoscopy. Patients were classified into the following four groups based on the changes in overall obesity from index to follow-up colonoscopy: non-obesity persisted (group 1), obesity to non-obesity (group 2), non-obesity to obesity (group 3), and obesity persisted (group 4). Patients were also divided into another four groups based on similar changes in abdominal obesity (groups 5-8). The number of patients in groups 1, 2, 3, and 4 was 5074, 457, 643, and 3538, respectively, and that in groups 5, 6, 7, and 8 was 4229, 538, 656, and 2189, respectively. Group 4 had a significantly higher risk of metachronous CRN compared to groups 1 and 2. However, metachronous advanced CRN (ACRN) risk was not different among groups 1, 2, 3, and 4. Metachronous CRN risk in group 8 (abdominal obesity persisted) was higher than that in groups 5 (non-abdominal obesity persisted) and 7 (non-abdominal obesity to abdominal obesity), and tended to be higher than that in group 6 (abdominal obesity to non-abdominal obesity). Additionally, group 8 had a significantly higher risk of metachronous ACRN compared to groups 5, 6, and 7. Changes in obesity affected the metachronous CRN risk. In particular, changes in abdominal obesity affected the metachronous ACRN risk.
Identifiants
pubmed: 32608201
pii: 61.579
doi: 10.3349/ymj.2020.61.7.579
pmc: PMC7329737
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
579-586Informations de copyright
© Copyright: Yonsei University College of Medicine 2020.
Déclaration de conflit d'intérêts
The authors have no potential conflicts of interest to disclose.
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