Effectiveness of Resistive Vibration Exercise and Whey Protein Supplementation Plus Alkaline Salt on the Skeletal Muscle Proteome Following 21 Days of Bed Rest in Healthy Males.

bed rest exercise insulin resistance mitochondrial metabolism nutrition protein degradation protein synthesis

Journal

Journal of proteome research
ISSN: 1535-3907
Titre abrégé: J Proteome Res
Pays: United States
ID NLM: 101128775

Informations de publication

Date de publication:
07 08 2020
Historique:
pubmed: 2 7 2020
medline: 22 6 2021
entrez: 2 7 2020
Statut: ppublish

Résumé

Muscle atrophy is a deleterious consequence of physical inactivity and is associated with increased morbidity and mortality. The aim of this study was to decipher the mechanisms involved in disuse muscle atrophy in eight healthy men using a 21 day bed rest with a cross-over design (control, with resistive vibration exercise (RVE), or RVE combined with whey protein supplementation and an alkaline salt (NEX)). The main physiological findings show a significant reduction in whole-body fat-free mass (CON -4.1%, RVE -4.3%, NEX -2.7%,

Identifiants

pubmed: 32609523
doi: 10.1021/acs.jproteome.0c00256
doi:

Substances chimiques

Proteome 0
Whey Proteins 0

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3438-3451

Auteurs

Helena C Kenny (HC)

3U Diabetes Partnership, School of Health and Human Performance, Dublin City University, Dublin 9, Ireland.
National Institute for Cellular and Biotechnology, Dublin City University, Dublin 9, Ireland.

Georg Tascher (G)

Département Sciences Analytiques, Université de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg 67087, France.
Centre National d'Etudes Spatiales (CNES), Paris 75001, France.
Institute of Biochemistry II, Goethe University Hospital, D-60590 Frankfurt am Main, Germany.

Anna Ziemianin (A)

Département Sciences Analytiques, Université de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg 67087, France.
Centre National d'Etudes Spatiales (CNES), Paris 75001, France.

Floriane Rudwill (F)

Départment d'Ecologie, Physiologie et Ethologie, Université de Strasbourg, Institut Pluridisiplinaire Hubert Curien. CNRS, UMR 7178, Strasbourg 67087, France.

Alexandre Zahariev (A)

Départment d'Ecologie, Physiologie et Ethologie, Université de Strasbourg, Institut Pluridisiplinaire Hubert Curien. CNRS, UMR 7178, Strasbourg 67087, France.

Isabelle Chery (I)

Départment d'Ecologie, Physiologie et Ethologie, Université de Strasbourg, Institut Pluridisiplinaire Hubert Curien. CNRS, UMR 7178, Strasbourg 67087, France.

Guillemette Gauquelin-Koch (G)

Centre National d'Etudes Spatiales (CNES), Paris 75001, France.

Marie-Pierre Barielle (MP)

Institut de Médecine et de Physiologie Spatiales, Toulouse 31400, France.

Martina Heer (M)

Profil, Hellersbergstrasse 9, Neuss D-41460, Germany.
Institute of Nutrition and Food Sciences, University of Bonn, Bonn D-53113, Germany.

Stephane Blanc (S)

Départment d'Ecologie, Physiologie et Ethologie, Université de Strasbourg, Institut Pluridisiplinaire Hubert Curien. CNRS, UMR 7178, Strasbourg 67087, France.

Donal J O'Gorman (DJ)

3U Diabetes Partnership, School of Health and Human Performance, Dublin City University, Dublin 9, Ireland.
National Institute for Cellular and Biotechnology, Dublin City University, Dublin 9, Ireland.

Fabrice Bertile (F)

Département Sciences Analytiques, Université de Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg 67087, France.

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Classifications MeSH