Synthesis of 3,4-Fused Tricyclic Indoles through Cascade Carbopalladation and C-H Amination: Development and Total Synthesis of Rucaparib.

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
02 07 2020
Historique:
entrez: 3 7 2020
pubmed: 3 7 2020
medline: 3 7 2020
Statut: ppublish

Résumé

3,4-Fused tricyclic indole scaffolds are ubiquitous in bioactive natural products and pharmaceuticals. A new protocol for the synthesis of 3,4-fused tricyclic indoles has been developed through cascade carbopalladation and C-H amination with

Identifiants

DOI: 10.1021/acs.orglett.0c01513 PMID: 32610935
pubmed: 32610935
doi: 10.1021/acs.orglett.0c01513
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4985-4989

Auteurs

Cang Cheng (C)

School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University 1239 Siping Road, Shanghai 200092, China.

Xiang Zuo (X)

School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University 1239 Siping Road, Shanghai 200092, China.

Dongdong Tu (D)

School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University 1239 Siping Road, Shanghai 200092, China.

Bin Wan (B)

School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University 1239 Siping Road, Shanghai 200092, China.

Yanghui Zhang (Y)

School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Tongji University 1239 Siping Road, Shanghai 200092, China.
ORCID: 0000-0003-2189-3496

Classifications MeSH