The Genotoxin Colibactin Shapes Gut Microbiota in Mice.
colibactin
enterobacteria
gut microbiota dysbiosis
microbiome
Journal
mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533
Informations de publication
Date de publication:
01 07 2020
01 07 2020
Historique:
entrez:
3
7
2020
pubmed:
3
7
2020
medline:
16
7
2021
Statut:
epublish
Résumé
The genotoxin colibactin produced by resident bacteria of the gut microbiota may have tumorigenic effect by inducing DNA double-strand breaks in host cells. Yet, the effect of colibactin on gut microbiota composition and functions remains unknown. To address this point, we designed an experiment in which pregnant mice were colonized with the following: (i) a commensal
Identifiants
pubmed: 32611705
pii: 5/4/e00589-20
doi: 10.1128/mSphere.00589-20
pmc: PMC7333578
pii:
doi:
Substances chimiques
Mutagens
0
Peptides
0
Polyketides
0
colibactin
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 Tronnet et al.
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