Impact of Coronary Atherosclerosis on Bioresorbable Vascular Scaffold Resorption and Vessel Wall Integration.
BVS, bioresorbable vascular scaffold
EES, everolimus-eluting stent
FHS, familial hypercholesterolemic swine
IVUS, intravascular ultrasonography
OCT, optical coherence tomography
bioresorbable vascular scaffolds
familial hypercholesterolemic swine
metallic drug-eluting stents
neoatherosclerosis
Journal
JACC. Basic to translational science
ISSN: 2452-302X
Titre abrégé: JACC Basic Transl Sci
Pays: United States
ID NLM: 101677259
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
20
12
2019
revised:
02
04
2020
accepted:
06
04
2020
entrez:
3
7
2020
pubmed:
3
7
2020
medline:
3
7
2020
Statut:
epublish
Résumé
The integration of the Absorb bioresorbable vascular scaffold (BVS) into the arterial wall has never been tested in an in vivo model of atherosclerosis. This study aimed to compare the long-term (up to 4 years) vascular healing responses of BVS to an everolimus-eluting metallic stent in the familial hypercholesterolemic swine model of atherosclerosis. The multimodality imaging and histology approaches indicate that the resorption and vascular integration profile of BVS is not affected by the presence of atherosclerosis. BVS demonstrated comparable long-term vascular healing and anti-restenotic efficacy to everolimus-eluting metallic stent but resulted in lower late lumen loss at 4 years.
Identifiants
pubmed: 32613147
doi: 10.1016/j.jacbts.2020.04.005
pii: S2452-302X(20)30166-2
pmc: PMC7315185
doi:
Types de publication
Journal Article
Langues
eng
Pagination
619-629Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 The Authors.
Références
Cardiovasc Interv Ther. 2012 Sep;27(3):141-54
pubmed: 22569783
Lancet. 2016 Mar 26;387(10025):1277-89
pubmed: 26825231
Int J Cardiovasc Imaging. 2015 Mar;31(3):471-82
pubmed: 25627777
Circulation. 2018 Jan 30;137(5):464-479
pubmed: 29089314
Cardiovasc Revasc Med. 2014 Mar;15(2):100-8
pubmed: 24603193
EuroIntervention. 2016 Dec 20;12(12):1510-1518
pubmed: 27998842
Coron Artery Dis. 2014 May;25(3):198-207
pubmed: 24642807
JACC Cardiovasc Interv. 2014 Jun;7(6):688-95
pubmed: 24835327
J Am Coll Cardiol. 2017 Nov 7;70(19):2330-2344
pubmed: 29096803
J Am Coll Cardiol. 2012 Jun 5;59(23):2051-7
pubmed: 22651862
J Am Coll Cardiol. 2015 Jun 16;65(23):2496-507
pubmed: 26065988
J Am Coll Cardiol. 2017 Jul 4;70(1):60-74
pubmed: 28662808
Eur Heart J Cardiovasc Pharmacother. 2019 Apr 1;5(2):105-116
pubmed: 30285099
Clin Cardiol. 2018 Jan;41(1):151-158
pubmed: 29369375
Lancet. 2017 Aug 19;390(10096):760-772
pubmed: 28732815
J Cardiovasc Magn Reson. 2011 Jan 26;13:10
pubmed: 21269470
J Vasc Surg. 2012 Dec;56(6):1680-8
pubmed: 22841285
Circ Cardiovasc Interv. 2014 Jun;7(3):330-42
pubmed: 24895447
Circulation. 2010 Nov 30;122(22):2288-300
pubmed: 20975003
J Am Coll Cardiol. 2015 Oct 27;66(17):1915-7
pubmed: 26493664
Eur Heart J. 2015 Aug 21;36(32):2147-59
pubmed: 25994755