The role of hepatitis B vaccine challenge dose in patients with underlying health conditions.


Journal

Human vaccines & immunotherapeutics
ISSN: 2164-554X
Titre abrégé: Hum Vaccin Immunother
Pays: United States
ID NLM: 101572652

Informations de publication

Date de publication:
01 02 2021
Historique:
pubmed: 3 7 2020
medline: 23 6 2021
entrez: 3 7 2020
Statut: ppublish

Résumé

We have evaluated the immunological response to Hepatitis B virus (HBV) booster vaccine dose in 129 adults with underlying diseases in comparison with 694 subjects at occupational risk of infection, who have previously completed the primary series and resulted with anti-HBs <10 mIU/mL. After booster dose, 60.5% of the patients with underlying diseases and 14.8% of the subjects at occupational risk resulted seronegative. By comparing two groups, rate of subjects with anamnestic response was higher in at occupational risk group respect to that at risk for medical conditions (OR: 5.99 [95%IC, 3.81-9.41],

Identifiants

pubmed: 32614653
doi: 10.1080/21645515.2020.1777058
pmc: PMC7899643
doi:

Substances chimiques

Hepatitis B Antibodies 0
Hepatitis B Surface Antigens 0
Hepatitis B Vaccines 0

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

575-579

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Auteurs

L Sticchi (L)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
Hygiene Unit, IRCCS Policlinico San Martino Hospital , Genoa, Italy.

I G Iavarone (IG)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.

P Durando (P)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
Occupational Medicine Unit, IRCCS Policlinico San Martino Hospital , Genoa, Italy.

A Di Biagio (A)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
Infectious Diseases, IRCCS Policlinico San Martino Hospital , Genoa, Italy.

I Schiavetti (I)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.

F Murgia (F)

Healthcare Profession Direction Operational Unit, IRCCS Policlinico San Martino Hospital , Genoa, Italy.

G Icardi (G)

Department of Health Sciences (Dissal), University of Genoa , Genoa, Italy.
Hygiene Unit, IRCCS Policlinico San Martino Hospital , Genoa, Italy.

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Classifications MeSH