Myocardial and Microvascular Injury Due to Coronavirus Disease 2019.
COVID-19
MI
microvascular dysfunction
microvascular injury
myocardial injury
Journal
European cardiology
ISSN: 1758-3764
Titre abrégé: Eur Cardiol
Pays: England
ID NLM: 101574780
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
18
05
2020
accepted:
30
05
2020
entrez:
4
7
2020
pubmed:
4
7
2020
medline:
4
7
2020
Statut:
epublish
Résumé
Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.
Identifiants
pubmed: 32617121
doi: 10.15420/ecr.2020.22
pmc: PMC7325215
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e52Informations de copyright
Copyright © 2020, Radcliffe Cardiology.
Déclaration de conflit d'intérêts
Disclosure: The authors have no conflicts of interest to declare.
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