Real-time assessment of COVID-19 prevalence among multiple sclerosis patients: a multicenter European study.


Journal

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 03 06 2020
accepted: 16 06 2020
pubmed: 4 7 2020
medline: 28 7 2020
entrez: 4 7 2020
Statut: ppublish

Résumé

We assessed the prevalence and impact of COVID-19 among multiple sclerosis (MS) patients across Europe by leveraging participant data collected as part of the ongoing EU IMI2 RADAR-CNS major programme aimed at finding new ways of monitoring neurological disorders using wearable devices and smartphone technology. In the present study, 399 patients of RADAR-MS have been included (mean age 43.9 years, 60.7% females) with 87/399 patients (21.8%) reporting major symptoms suggestive of COVID-19. A trend for an increased risk of COVID-19 symptoms under alemtuzumab and cladribine treatments in comparison to injectables was observed. Remote monitoring technologies may support health authorities in monitoring and containing the ongoing pandemic.

Identifiants

pubmed: 32617741
doi: 10.1007/s10072-020-04519-x
pii: 10.1007/s10072-020-04519-x
pmc: PMC7331489
doi:

Substances chimiques

Alemtuzumab 3A189DH42V

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1647-1650

Subventions

Organisme : Alzheimer's Society
ID : 171
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_17214
Pays : United Kingdom

Références

Nature. 2020 Mar;579(7798):270-273
pubmed: 32015507
Lancet. 2012 Nov 24;380(9856):1819-28
pubmed: 23122652
N Engl J Med. 2010 Feb 4;362(5):416-26
pubmed: 20089960
JMIR Mhealth Uhealth. 2019 Aug 01;7(8):e11734
pubmed: 31373275
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264

Auteurs

Gloria Dalla Costa (G)

Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy.
Neurorehabilitation Unit, IRCCS Ospedale San Raffaele, Milan, Italy.

Letizia Leocani (L)

Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy.
Neurorehabilitation Unit, IRCCS Ospedale San Raffaele, Milan, Italy.

Xavier Montalban (X)

Multiple Sclerosis Centre of Catalonia (Cemcat), Department of Neurology/Neuroimmunology, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

Ana Isabel Guerrero (AI)

Multiple Sclerosis Centre of Catalonia (Cemcat), Department of Neurology/Neuroimmunology, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

Per Soelberg Sørensen (PS)

Danish Multiple Sclerosis Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

Melinda Magyari (M)

Danish Multiple Sclerosis Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

Richard J B Dobson (RJB)

The Department of Biostatistics and Health informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Institute of Health Informatics, University College London, London, UK.

Nicholas Cummins (N)

Embedded Intelligence for Health Care & Wellbeing, University of Augsburg, Augsburg, Germany.

Vaibhav A Narayan (VA)

Janssen Research and Development, LLC, Titusville, NJ, USA.

Matthew Hotopf (M)

The Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Giancarlo Comi (G)

Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy. comi.giancarlo@hsr.it.

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Classifications MeSH