Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India.
Adult
Alcohol Drinking
/ physiopathology
Antitubercular Agents
/ therapeutic use
Case-Control Studies
Female
Follow-Up Studies
Humans
India
Logistic Models
Lost to Follow-Up
Male
Marital Status
Middle Aged
Mycobacterium tuberculosis
/ isolation & purification
Risk Factors
Tuberculosis, Pulmonary
/ drug therapy
Journal
The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
4
7
2020
medline:
11
11
2020
entrez:
4
7
2020
Statut:
ppublish
Résumé
Identifying predictors of loss to follow-up (LTFU; treatment lapse ≥ 2 months) among people with tuberculosis (TB) may assist programmatic efforts in controlling the spread of TB. Newly diagnosed smear-positive TB patients were enrolled in the Regional Prospective Observational Research for TB study in Puducherry and Tamil Nadu, India. Treatment records were used to identify LTFU of those who were enrolled from May 2014 through December 2017. This nested case-control study evaluated male TB patients. Predictors were assessed using multivariable logistic regression. Of 425 men with TB, 82 (19%) were LTFU. In the adjusted analyses of males, divorced/separated marital status (adjusted odds ratio [aOR] 3.80; 95% CI: 1.39-10.38) and at-risk alcohol use (aOR 1.92; 95% CI: 1.12-3.27) were significant predictors for increased risk of LTFU, and diabetes was a significant predictor for decreased risk of LTFU (aOR 0.52; 95% CI: 0.29-0.92). Of 53 men with recorded date of last treatment visit, 23 (43%) and 43 (81%) had LTFU within the first 2 and first 4 months of treatment, respectively. Addressing at-risk alcohol use and providing more intensive follow-up could lead to improved treatment completion.
Identifiants
pubmed: 32618243
doi: 10.4269/ajtmh.19-0415
pmc: PMC7470548
pii: tpmd190415
doi:
pii:
Substances chimiques
Antitubercular Agents
0
Types de publication
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
1050-1056Références
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