Effect of the Phytochemical Agents against the SARS-CoV and Some of them Selected for Application to COVID-19: A Mini-Review.
Alkaloids
/ isolation & purification
Animals
Antiviral Agents
/ isolation & purification
COVID-19
/ epidemiology
Curcuma
Humans
Middle East Respiratory Syndrome Coronavirus
/ drug effects
Nigella sativa
Phytochemicals
/ isolation & purification
Plant Extracts
/ isolation & purification
Plants, Medicinal
Severe acute respiratory syndrome-related coronavirus
/ drug effects
SARS-CoV-2
/ drug effects
Scutellaria baicalensis
COVID-19 Drug Treatment
COVID-19
China
MERS-CoV
SARS-CoV
anti-coronavirus
medicinal plants
phytochemicals
viral pneumonia
Journal
Current pharmaceutical biotechnology
ISSN: 1873-4316
Titre abrégé: Curr Pharm Biotechnol
Pays: Netherlands
ID NLM: 100960530
Informations de publication
Date de publication:
2021
2021
Historique:
received:
25
03
2020
revised:
12
04
2020
accepted:
14
06
2020
pubmed:
4
7
2020
medline:
1
6
2021
entrez:
4
7
2020
Statut:
ppublish
Résumé
The aim of the present review is to provide basic knowledge regarding the treatment of Coronavirus via medicinal plants. Coronavirus (COVID-19, SARS-CoV, and MERS-CoV) as a viral pneumonia causative agent, has infected thousands of people in China and worldwide. Currently, there is no specific medicine or vaccine available that can treat or prevent this virus and this has posed a severe threat to human health; therefore, there is an urgent need to develop a novel drug or anticoronavirus vaccine. However, natural compounds to treat coronaviruses are the most effective alternative and complementary therapies due to their diverse range of biological and therapeutic properties. We performed an open-ended, English restricted search of Scopus database, Web of Science, and Pubmed for all available literature from Jan-March, 2020, using terms related to phytochemical compounds, medicinal plants and coronavirus. The view on anti-coronavirus (anti-CoV) activity in the plant-derived phytochemicals and medicinal plants gives a strong base to develop a novel treatment employing these compounds for coronavirus. Various phytochemicals and medicinal plant extracts have been revised and are considered as potential anti-CoV agents for effective control of the virus and future drug development. Herein, we discuss some important plants (Scutellaria baicalensis, Psorothamnus arborescens, Glycyrrhiza radix, Glycyrrhiza uralensis, Lycoris radiate, Phyllanthus emblica, Camellia sinensis, Hyptis atrorubens Poit, Fraxinus sieboldiana, Erigeron breviscapus, Citri Reticulatae Pericarpium, Amaranthus tricolor, Phaseolus vulgaris, Rheum palmatum, Curcuma longa and Myrica cerifera) that have emerged to have broad-spectrum antiviral activity. Nigella sativa has potent anti-SARS-CoV activity and it might be a useful source for developing novel antiviral therapies for coronavirus.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of the present review is to provide basic knowledge regarding the treatment of Coronavirus via medicinal plants. Coronavirus (COVID-19, SARS-CoV, and MERS-CoV) as a viral pneumonia causative agent, has infected thousands of people in China and worldwide. Currently, there is no specific medicine or vaccine available that can treat or prevent this virus and this has posed a severe threat to human health; therefore, there is an urgent need to develop a novel drug or anticoronavirus vaccine. However, natural compounds to treat coronaviruses are the most effective alternative and complementary therapies due to their diverse range of biological and therapeutic properties.
METHODS
METHODS
We performed an open-ended, English restricted search of Scopus database, Web of Science, and Pubmed for all available literature from Jan-March, 2020, using terms related to phytochemical compounds, medicinal plants and coronavirus.
RESULTS
RESULTS
The view on anti-coronavirus (anti-CoV) activity in the plant-derived phytochemicals and medicinal plants gives a strong base to develop a novel treatment employing these compounds for coronavirus. Various phytochemicals and medicinal plant extracts have been revised and are considered as potential anti-CoV agents for effective control of the virus and future drug development. Herein, we discuss some important plants (Scutellaria baicalensis, Psorothamnus arborescens, Glycyrrhiza radix, Glycyrrhiza uralensis, Lycoris radiate, Phyllanthus emblica, Camellia sinensis, Hyptis atrorubens Poit, Fraxinus sieboldiana, Erigeron breviscapus, Citri Reticulatae Pericarpium, Amaranthus tricolor, Phaseolus vulgaris, Rheum palmatum, Curcuma longa and Myrica cerifera) that have emerged to have broad-spectrum antiviral activity.
CONCLUSION
CONCLUSIONS
Nigella sativa has potent anti-SARS-CoV activity and it might be a useful source for developing novel antiviral therapies for coronavirus.
Identifiants
pubmed: 32619167
pii: CPB-EPUB-107892
doi: 10.2174/1389201021666200703201458
doi:
Substances chimiques
Alkaloids
0
Antiviral Agents
0
Phytochemicals
0
Plant Extracts
0
Scutellaria baicalensis extract
0
turmeric extract
856YO1Z64F
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
444-450Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.