CORDITE: The Curated CORona Drug InTERactions Database for SARS-CoV-2.
Bioinformatics
Biological Database
Drugs
Medicine
Virology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
24 Jul 2020
24 Jul 2020
Historique:
received:
04
05
2020
revised:
09
06
2020
accepted:
15
06
2020
pubmed:
4
7
2020
medline:
4
7
2020
entrez:
4
7
2020
Statut:
ppublish
Résumé
Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 virus based on de novo drug design and drug repurposing. The former approach is very time consuming and needs extensive testing in humans, whereas drug repurposing is more promising, as the drugs have already been tested for side effects, etc. At present, there is no treatment for COVID-19 that is clinically effective, but there is a huge amount of data from studies that analyze potential drugs. We developed CORDITE to efficiently combine state-of-the-art knowledge on potential drugs and make it accessible to scientists and clinicians. The web interface also provides access to an easy-to-use API that allows a wide use for other software and applications, e.g., for meta-analysis, design of new clinical studies, or simple literature search. CORDITE is currently empowering many scientists across all continents and accelerates research in the knowledge domains of virology and drug design.
Identifiants
pubmed: 32619700
pii: S2589-0042(20)30484-3
doi: 10.1016/j.isci.2020.101297
pmc: PMC7305714
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101297Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Interests The authors declare no competing interests.
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