Impact of Point-of-care Testing on Length of Stay of Patients in the Emergency Department: A Cluster-randomized Controlled Study.


Journal

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
ISSN: 1553-2712
Titre abrégé: Acad Emerg Med
Pays: United States
ID NLM: 9418450

Informations de publication

Date de publication:
10 2020
Historique:
received: 11 02 2020
revised: 25 06 2020
accepted: 25 06 2020
pubmed: 6 7 2020
medline: 23 1 2021
entrez: 5 7 2020
Statut: ppublish

Résumé

Crowding is a frequent concern in the emergency department (ED). Laboratory point-of-care testing (POCT) has been proposed to decrease patients' length of stay (LOS). Our objective was to determine whether an extended panel of POCT solutions could reduce LOS. This was a single-center, prospective, open-label, controlled cluster-randomized study. Blood test processing was randomized into 1-week inclusion periods: interventional arm (laboratory analyses performed on POCT analyzers implemented in the ED) or control arm (central laboratory). The primary endpoint was LOS of patients in the ED. Secondary endpoints were time to result (TTR), ED crowding surrogates, and average total cost of an ED visit in each arm. A total of 23,231 patients were included and 20,923 were analyzed for the main outcome measure. Mean ± SD age was 46 ± 20 years, and 7,905 (36%) underwent blood sampling. Mean ± SD LOSs were 203 ± 161 and 210 ± 168 minutes in the POCT and control arms, respectively. LOS reduction for the entire ED population was -9 minutes (95% confidence interval [CI] = -22 to 5, p = 0.22) compared to the control arm and -17 minutes (95% CI = -34.0 to 0.6, p = 0.06) for patients undergoing blood sampling. The mean ± SD TTRs were 28 ± 31 and 79 ± 34 minutes in the POCT and control arms, respectively (TTR reduction = -51 minutes, 95% CI = -54 to -48 minutes, p < 0.001). The implementation of an extended panel of POCT solutions in an ED did not significantly reduce the LOS, but reduced the TTR.

Identifiants

pubmed: 32621374
doi: 10.1111/acem.14072
doi:

Banques de données

ClinicalTrials.gov
['NCT03840564']

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

974-983

Informations de copyright

© 2020 by the Society for Academic Emergency Medicine.

Références

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Auteurs

Pierre Hausfater (P)

From the, Emergency Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.
the, UMR INSERM 1166, IHU ICAN, Sorbonne Université, GRC-14 BIOSFAST, Paris, France.

David Hajage (D)

the, Département Biostatistique Santé Publique et Information Médicale, Centre de Pharmacoépidémiologie (Cephepi), Sorbonne Université, APHP, Paris, France.

Julie Bulsei (J)

the, AP-HP URC Eco Ile de France Hôpital de l'Hôtel Dieu, Paris, France.
the, CRESS, INSERM, INRA, Université de Paris, Paris, France.

Pauline Canavaggio (P)

From the, Emergency Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.

Alexandre Lafourcade (A)

the, Unité de Recherche Clinique Salpêtrière-Charles Foix, APHP, Paris, France.

Anne Laure Paquet (AL)

From the, Emergency Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.

Michel Arock (M)

the, Sorbonne Université, Paris, France.
and the, Biochemisty and Emergency Biology Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.

Isabelle Durand-Zaleski (I)

the, AP-HP URC Eco Ile de France Hôpital de l'Hôtel Dieu, Paris, France.
the, CRESS, INSERM, INRA, Université de Paris, Paris, France.

Bruno Riou (B)

From the, Emergency Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.
the, UMR INSERM 1166, IHU ICAN, Sorbonne Université, GRC-14 BIOSFAST, Paris, France.

Nathalie Oueidat (N)

and the, Biochemisty and Emergency Biology Department, Hôpital Pitié-Salpêtrière, APHP, Paris, France.

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