Ability of 24-2C and 24-2 Grids to Identify Central Visual Field Defects and Structure-Function Concordance in Glaucoma and Suspects.
Aged
Cross-Sectional Studies
Female
Glaucoma, Open-Angle
/ diagnosis
Humans
Intraocular Pressure
Male
Middle Aged
Nerve Fibers
/ pathology
Ocular Hypertension
/ diagnosis
Optic Disk
/ pathology
Optic Nerve Diseases
/ diagnosis
Prospective Studies
Retinal Ganglion Cells
/ pathology
Tomography, Optical Coherence
Tonometry, Ocular
Vision Disorders
/ diagnosis
Visual Field Tests
/ methods
Visual Fields
/ physiology
Journal
American journal of ophthalmology
ISSN: 1879-1891
Titre abrégé: Am J Ophthalmol
Pays: United States
ID NLM: 0370500
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
15
04
2020
revised:
11
06
2020
accepted:
18
06
2020
pubmed:
6
7
2020
medline:
22
12
2020
entrez:
5
7
2020
Statut:
ppublish
Résumé
The purpose of this study was to compare the ability of the 24-2 test grid with that of the 24-2C test grid to measure visual field global indices, identify central visual field defects, and facilitate macular structure-function analysis with optical coherence tomography (OCT) scans in glaucoma suspects and glaucoma patients. Prospective, cross-sectional study. One eye from each of 100 glaucoma suspects and glaucoma patients (60 undergoing SITA-Faster [Zeiss Meditec] testing on 24-2 and 24-2C; 40 undergoing SITA-Standard [Zeiss Meditec] testing on 24-2 and SITA-Faster on 24-2C) were included in the study. Global visual field indices, test duration, and pattern deviation results were extracted. The deviation map from the Cirrus OCT (Carl Zeiss Meditec) Ganglion Cell Analysis (GCA) was extracted, and structure-function relationships were compared after correction of the visual field test stimulus location that stimulated the corresponding retinal ganglion cell. Global index results of the 24-2 grid were similar to those of the 24-2C grid, and both identified a comparable number of clusters of visual field defects. Centrally, the 24-2C grid identified more clusters of defects than the 24-2 grid, but this was not statistically significant. Although the 24-2C test locations resulted in more instances of structure-function concordance than the 24-2 locations, half the locations in the 24-2C grid fell close to or outside the GCA grid when corrected for ganglion cell displacement. The 24-2C returned global visual field indices similar to the 24-2 grid but tended to identify more clusters of central functional defects. Central structure-function concordance was better achieved using the 24-2C grid, but half of the visual field test locations did not coincide with the commonly used macular thickness scan.
Identifiants
pubmed: 32621896
pii: S0002-9394(20)30320-2
doi: 10.1016/j.ajo.2020.06.024
pii:
doi:
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
317-331Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.