Hyperinflation With Pulmonary Dysfunction in Donor Lungs With Smoking History During Lung Perfusion.
Cigarette use
Donor lung
Emphysema
Overexpansion
Smoking injury
Journal
The Journal of surgical research
ISSN: 1095-8673
Titre abrégé: J Surg Res
Pays: United States
ID NLM: 0376340
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
22
01
2020
revised:
31
03
2020
accepted:
06
05
2020
pubmed:
6
7
2020
medline:
15
12
2020
entrez:
5
7
2020
Statut:
ppublish
Résumé
Donor lungs with smoking history are perfused in ex vivo lung perfusion (EVLP) to expand donor lung pool. However, the impact of hyperinflation of perfused lungs in EVLP remains unknown. The aim of this study was to investigate the significance of hyperinflation, using an ex vivo measurement delta V Seventeen rejected donor lungs with smoking history of median 10 pack-years were perfused for 2 h in cellular EVLP. Hyperinflation was evaluated by measuring delta V The positive delta V Positive delta V
Sections du résumé
BACKGROUND
Donor lungs with smoking history are perfused in ex vivo lung perfusion (EVLP) to expand donor lung pool. However, the impact of hyperinflation of perfused lungs in EVLP remains unknown. The aim of this study was to investigate the significance of hyperinflation, using an ex vivo measurement delta V
MATERIALS AND METHODS
Seventeen rejected donor lungs with smoking history of median 10 pack-years were perfused for 2 h in cellular EVLP. Hyperinflation was evaluated by measuring delta V
RESULTS
The positive delta V
CONCLUSIONS
Positive delta V
Identifiants
pubmed: 32622165
pii: S0022-4804(20)30292-4
doi: 10.1016/j.jss.2020.05.019
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
502-509Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.