Effects of alkaline agents on respiratory characteristics in rabbit models of respiratory failure.

Acute Lung Injury / physiopathology Animals Buffers Disease Models, Animal Hypercapnia / physiopathology Inhalation / drug effects Pressure Rabbits Respiratory Insufficiency / physiopathology Respiratory Rate / drug effects Sodium Bicarbonate / pharmacology Tidal Volume / drug effects Tromethamine / pharmacology Work of Breathing / drug effects
Hypercapnia Lung injury NaHCO(3) inspiratory effort Transpulmonary pressure Trometamol

Journal

Respiratory physiology & neurobiology
ISSN: 1878-1519
Titre abrégé: Respir Physiol Neurobiol
Pays: Netherlands
ID NLM: 101140022

Informations de publication

Date de publication:
09 2020
Historique:
received: 10 04 2020
revised: 22 06 2020
accepted: 25 06 2020
pubmed: 6 7 2020
medline: 6 10 2021
entrez: 6 7 2020
Statut: ppublish

Résumé

This study aimed to investigate the effects of alkaline agents on reducing strong inspiratory effort. Rabbits with hypercapnia or lung injury, induced via repeated lung lavage following injurious ventilation, were treated with Saline, NaHCO

Identifiants

DOI: 10.1016/j.resp.2020.103485 PMID: 32622903
pubmed: 32622903
pii: S1569-9048(20)30143-9
doi: 10.1016/j.resp.2020.103485
pii:
doi:

Substances chimiques

Buffers 0
Tromethamine 023C2WHX2V
Sodium Bicarbonate 8MDF5V39QO

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

103485

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Tomonori Yamashita (T)

Department of Anesthesiology, Osaka Women's and Children's Hospital, Izumi, Japan.

Akinori Uchiyama (A)

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan. Electronic address: auchiyama@hp-icu.med.osaka-u.ac.jp.

Yukiko Koyama (Y)

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Takeshi Yoshida (T)

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Aiko Tanaka (A)

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Yuji Fujino (Y)

Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

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Classifications MeSH

questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Lésion pulmonaire aigüe › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Eucaryotes › Animaux › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Substances tampon › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Effects of alkaline agents on respiratory...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes respiratoires › Hypercapnie › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Respiration › Mécanique respiratoire › Inspiration › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Pression › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Lagomorpha › Lapins › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Troubles respiratoires › Insuffisance respiratoire › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Respiration › Fréquence respiratoire › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du sodium › Hydrogénocarbonate de sodium › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Capacité pulmonaire totale › Capacité vitale › Capacité inspiratoire › Volume courant › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Composés chimiques organiques › Alcools › Glycols › Propylène glycols › Trométhamine › Effects of alkaline agents on respiratory...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Travail respiratoire › Effects of alkaline agents on respiratory...