Comparison of optimal screw configurations in two locking plate systems for proximal humerus fixation - a finite element analysis study.


Journal

Clinical biomechanics (Bristol, Avon)
ISSN: 1879-1271
Titre abrégé: Clin Biomech (Bristol, Avon)
Pays: England
ID NLM: 8611877

Informations de publication

Date de publication:
08 2020
Historique:
received: 26 02 2020
revised: 08 06 2020
accepted: 22 06 2020
pubmed: 6 7 2020
medline: 23 4 2021
entrez: 6 7 2020
Statut: ppublish

Résumé

Management of proximal humerus fractures is challenging, especially in elderly. Locking plating is a common surgical treatment option. The Proximal Humerus Internal Locking System (plate-A) has shown to lower complication rates compared to conventional plates, but is associated with impingement risk, which could be avoided using Peri-articular Proximal Humerus Plate (plate-B). Nevertheless, biomechanical performance and optimal screw configuration of plate-B is unknown. The aim of this study was to evaluate different screw configurations of plate-B and compare with plate-A using finite element analyses. Twenty-six proximal humerus models were osteotomised to create unstable three-part fractures, fixed with either of the two plates, and tested under three anatomical loading conditions using a previous established and validated finite element simulation framework. Various clinically relevant screw configurations were investigated for both plates and compared based on the predicted peri-implant bone strain, being a validated surrogate of cyclic cut-out failure. Besides increasing the number of screws, the placement of the posterior screws in combination with the calcar screw in the plate-B significantly decreased the predicted failure risk. Generally, plate-A had a lower predicted failure risk than plate-B. The posterior and calcar screws may be prioritized in plate-B. Compared to plate-A, the more distal positioning, less purchase in the posterior aspect and a smaller screw spread due to not fitting of the most distal calcar screw in most investigated subjects led to a significantly higher predicted failure risk for most plate-B configurations. The findings of the simulations study require clinical corroboration.

Sections du résumé

BACKGROUND
Management of proximal humerus fractures is challenging, especially in elderly. Locking plating is a common surgical treatment option. The Proximal Humerus Internal Locking System (plate-A) has shown to lower complication rates compared to conventional plates, but is associated with impingement risk, which could be avoided using Peri-articular Proximal Humerus Plate (plate-B). Nevertheless, biomechanical performance and optimal screw configuration of plate-B is unknown. The aim of this study was to evaluate different screw configurations of plate-B and compare with plate-A using finite element analyses.
METHODS
Twenty-six proximal humerus models were osteotomised to create unstable three-part fractures, fixed with either of the two plates, and tested under three anatomical loading conditions using a previous established and validated finite element simulation framework. Various clinically relevant screw configurations were investigated for both plates and compared based on the predicted peri-implant bone strain, being a validated surrogate of cyclic cut-out failure.
FINDINGS
Besides increasing the number of screws, the placement of the posterior screws in combination with the calcar screw in the plate-B significantly decreased the predicted failure risk. Generally, plate-A had a lower predicted failure risk than plate-B.
INTERPRETATION
The posterior and calcar screws may be prioritized in plate-B. Compared to plate-A, the more distal positioning, less purchase in the posterior aspect and a smaller screw spread due to not fitting of the most distal calcar screw in most investigated subjects led to a significantly higher predicted failure risk for most plate-B configurations. The findings of the simulations study require clinical corroboration.

Identifiants

pubmed: 32623297
pii: S0268-0033(20)30215-1
doi: 10.1016/j.clinbiomech.2020.105097
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

105097

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors are not compensated and there are no other institutional subsidies, corporate affiliations, or funding sources supporting this work unless clearly documented and disclosed.

Auteurs

Dominic Mischler (D)

AO Research Institute Davos, Davos, Switzerland. Electronic address: dominic.mischler@aofoundation.org.

Satish Babu (S)

Trauma and Orthopaedic Department, Frimley Park Hospital, Camberley, UK.

Georg Osterhoff (G)

Department of Orthopaedics, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.

Carlotta Pari (C)

Orthopaedic, and Trauma Department, Santa Maria Delle Croci Hospital, Ravenna, Italy.

James Fletcher (J)

AO Research Institute Davos, Davos, Switzerland; Department for Health, University of Bath, Bath, UK.

Markus Windolf (M)

AO Research Institute Davos, Davos, Switzerland.

Boyko Gueorguiev (B)

AO Research Institute Davos, Davos, Switzerland.

Peter Varga (P)

AO Research Institute Davos, Davos, Switzerland.

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Classifications MeSH