Use of Intense Pulsed Light to Mitigate Meibomian Gland Dysfunction for Dry Eye Disease.
dry eye disease
intense pulsed light
mechanism of action
meibomian gland dysfunction
meibum
Journal
International journal of medical sciences
ISSN: 1449-1907
Titre abrégé: Int J Med Sci
Pays: Australia
ID NLM: 101213954
Informations de publication
Date de publication:
2020
2020
Historique:
received:
25
01
2020
accepted:
24
05
2020
entrez:
7
7
2020
pubmed:
7
7
2020
medline:
9
3
2021
Statut:
epublish
Résumé
Dry Eye Disease (DED) is a common ocular condition that needs prompt diagnosis and careful treatment interventions. If left untreated, it can lead to numerous sight-threatening complications, including ulceration of the cornea, blepharitis, alterations of the tear film, conjunctivitis, and in severe cases, may lead to scarring, thinning, and even perforation of the cornea. Intense pulsed light (IPL) is a non-laser high-intensity light source that has shown to play a valuable role in dry eye disease. Recent evidence from various research works has shown that IPL modifies the mechanism of meibomian gland dysfunction (MGD), which helps to relieve the symptoms of DED. In this review, we demonstrated the mechanism of action of IPL, including its benefits on DED. The emerging evidence shows that the role of IPL in DED is novel and therapeutic. These results direct us to conclude that IPL is a potentially beneficial tool and essential future therapy for dry eye disease. Advances in the treatment of DED will lead to a better quality of life. However, tools to recognize potentially severe side effects of DED earlier in order to treat or prevent them must be developed.
Identifiants
pubmed: 32624695
doi: 10.7150/ijms.44288
pii: ijmsv17p1385
pmc: PMC7330664
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1385-1392Informations de copyright
© The author(s).
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
Références
Zhonghua Yan Ke Za Zhi. 2017 Sep 11;53(9):675-681
pubmed: 28926885
Photomed Laser Surg. 2018 Oct;36(10):562-567
pubmed: 30251914
Ophthalmologe. 2019 Oct;116(10):982-988
pubmed: 31535189
Ocul Surf. 2020 Apr;18(2):286-297
pubmed: 32007523
Cornea. 2016 Mar;35(3):318-22
pubmed: 26785301
Cornea. 2018 Sep;37(9):1155-1158
pubmed: 29708939
Am J Ophthalmol. 2017 Nov;183:81-90
pubmed: 28887117
Cornea. 2018 Dec;37(12):1566-1571
pubmed: 30004962
Lasers Surg Med. 2002;30(2):82-5
pubmed: 11870785
Front Biosci. 2001 Oct 01;6:D1192-206
pubmed: 11578969
Diagnostics (Basel). 2019 Oct 13;9(4):
pubmed: 31614910
J Ophthalmic Vis Res. 2019 Jan-Mar;14(1):3-10
pubmed: 30820280
Can J Ophthalmol. 2020 Jun;55(3):189-198
pubmed: 31941589
Clin Microbiol Infect. 2012 Oct;18(10):1020-5
pubmed: 22114987
J Ophthalmol. 2019 Sep 16;2019:3143469
pubmed: 31637051
Eye Contact Lens. 2020 Jan;46(1):3-16
pubmed: 31834043
Cornea. 2020 Mar;39(3):325-332
pubmed: 31764289
Can J Ophthalmol. 2016 Aug;51(4):249-253
pubmed: 27521662
Int Ophthalmol. 2014 Dec;34(6):1291-301
pubmed: 25416345
Invest Ophthalmol Vis Sci. 2015 Feb 12;56(3):1965-70
pubmed: 25678687
Optom Vis Sci. 2012 May;89(5):E760-9
pubmed: 22488268
Clin Ophthalmol. 2017 May 02;11:817-827
pubmed: 28496300
Immunol Allergy Clin North Am. 2008 Feb;28(1):105-17, vi-vii
pubmed: 18282548
Trans Am Ophthalmol Soc. 2008;106:336-56
pubmed: 19277245
J Ophthalmol. 2016;2016:1910694
pubmed: 27413540
Br J Ophthalmol. 2016 Mar;100(3):300-6
pubmed: 26781133
Science. 1983 Apr 29;220(4596):524-7
pubmed: 6836297
Photobiomodul Photomed Laser Surg. 2019 Feb;37(2):70-76
pubmed: 31050931
Photomed Laser Surg. 2015 Jan;33(1):41-6
pubmed: 25594770
Int Ophthalmol. 2020 Jul;40(7):1695-1705
pubmed: 32200506
Curr Eye Res. 2018 Mar;43(3):308-313
pubmed: 29199865
Cochrane Database Syst Rev. 2020 Mar 18;3:CD013559
pubmed: 32182637
Int Rev Cytol. 2003;231:1-49
pubmed: 14713002
Clin Optom (Auckl). 2019 Oct 17;11:113-126
pubmed: 31802961
J Invest Dermatol. 2009 Dec;129(12):2751-9
pubmed: 19587693
Arch Soc Esp Oftalmol. 2017 Nov;92(11):509-515
pubmed: 28256362
Graefes Arch Clin Exp Ophthalmol. 1995 Nov;233(11):694-8
pubmed: 8566825
Cont Lens Anterior Eye. 2018 Oct;41(5):430-435
pubmed: 29958778
Ophthalmology. 2017 Nov;124(11S):S20-S26
pubmed: 29055358
Br J Dermatol. 2007 Sep;157(3):474-81
pubmed: 17596156
Zhonghua Yan Ke Za Zhi. 2018 Feb 11;54(2):140-143
pubmed: 29429299
Photobiomodul Photomed Laser Surg. 2020 Jan 27;:
pubmed: 31985328
J Cosmet Laser Ther. 2019;21(6):316-322
pubmed: 31018716
Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):505-10
pubmed: 20689407
Lasers Surg Med. 2007 Feb;39(2):132-9
pubmed: 17066482
J Photochem Photobiol B. 1999 Mar;49(1):1-17
pubmed: 10365442
Lasers Surg Med. 1989;9(5):497-505
pubmed: 2811573
Sci Rep. 2019 May 21;9(1):7648
pubmed: 31113979
Ann Anat. 2015 Mar;198:66-72
pubmed: 25547460
Curr Opin Ophthalmol. 2015 Jul;26(4):314-8
pubmed: 26058031
Photomed Laser Surg. 2018 Jun;36(6):326-332
pubmed: 29688838
Ocul Surf. 2004 Apr;2(2):131-48
pubmed: 17216084
Eur J Ophthalmol. 2020 Mar;30(2):289-292
pubmed: 30514116
Lasers Surg Med. 2003;32(2):78-87
pubmed: 12561039
Ophthalmology. 2010 May;117(5):870-877.e1
pubmed: 20079929
Lasers Surg Med. 2005 Apr;36(4):270-80
pubmed: 15719420
Int Ophthalmol. 2020 May;40(5):1135-1141
pubmed: 31916061
J Nippon Med Sch. 2006 Apr;73(2):75-81
pubmed: 16641531
Br J Dermatol. 2012 Nov;167(5):1032-6
pubmed: 22709541
BMC Ophthalmol. 2019 Oct 28;19(1):211
pubmed: 31660904
Clin Ophthalmol. 2017 Jun 20;11:1167-1173
pubmed: 28790801
Br J Dermatol. 2008 Sep;159(3):628-32
pubmed: 18565174
Ocul Surf. 2019 Jan;17(1):104-110
pubmed: 30445177
Photomed Laser Surg. 2005 Aug;23(4):355-61
pubmed: 16144476
Ocul Surf. 2017 Jul;15(3):438-510
pubmed: 28736340
Int J Ophthalmol. 2019 Nov 18;12(11):1708-1713
pubmed: 31741858
Curr Med Sci. 2019 Oct;39(5):800-809
pubmed: 31612399
Ocul Surf. 2019 Apr;17(2):310-317
pubmed: 30528291
Invest Ophthalmol Vis Sci. 2011 Mar 30;52(4):1938-78
pubmed: 21450915
J Vis Exp. 2019 Apr 1;(146):
pubmed: 30985743